SCHEMBL29935362

SCHEMBL29935362

Cc1nc(C=O)ccc1O

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 1/20 0.46
ALDH1A1 P00352 4/20 0.37
ERN1 O75460 9/20 0.37
HTR2B P41595 2/20 0.37
KDM4E B2RXH2 3/20 0.35
PTGS2 P35354 1/20 0.35
RAB9A P51151 1/20 0.35
HPGD P15428 2/20 0.35
GAA P10253 1/20 0.35
STAT3 P40763 1/20 0.35
RRM2 P31350 1/20 0.34
TERT O14746 1/20 0.34
TRIM24 O15164 1/20 0.33
ALDH5A1 P51649 1/20 0.33
ABAT P80404 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
TRIM33 Q9UPN9 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22164783 0.78 KDM4E (0.35) ALDH1A1KDM4EHPGDGAASTAT3
SCHEMBL31052928 0.78 KDM4E (0.35) ALDH1A1KDM4EHPGDGAASTAT3
SCHEMBL24983588 0.77 CCR1 (0.50) CCR1ALDH1A1ERN1HTR2BKDM4E
SCHEMBL6629423 0.77 CCR1 (0.50) CCR1ALDH1A1ERN1HTR2BRRM2
SCHEMBL2494195 0.76 CCR1 (0.48) CCR1ALDH1A1ERN1HTR2BKDM4E
SCHEMBL29956915 0.75 CCR1 (0.43) CCR1ALDH1A1ERN1KDM4ERRM2
SCHEMBL1979692 0.74 CCR1 (0.46) CCR1ALDH1A1ERN1HTR2BKDM4E
SCHEMBL16742704 0.74 CCR1 (0.46) CCR1ALDH1A1ERN1HTR2BKDM4E
SCHEMBL21817861 0.74 CCR1 (0.46) CCR1ALDH1A1ERN1RRM2TERT
SCHEMBL13723445 0.74 CCR1 (0.46) CCR1ALDH1A1ERN1RRM2TERT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4096661-A1 COMPOUNDS AND COMPOSITIONS FOR USE IN TREATING SKIN DISORDERS Kamari Pharma Ltd. (IL) 2022-12-07 EP claimed
US-12435061-B2 Compounds and compositions for use in treating skin disorders KAMARI PHARMA LTD. (IL) 2025-10-07 US disclosed
EP-4574822-A2 COMPOUNDS AND COMPOSITIONS FOR USE IN TREATING SKIN DISORDERS Kamari Pharma Ltd. (IL) 2025-06-25 EP disclosed
CN-118702672-A Compounds and compositions for treating skin disorders 卡玛瑞制药有限公司 2024-09-27 CN disclosed
CN-115335050-B Compounds and compositions for treating skin disorders 卡玛瑞制药有限公司 2024-05-17 CN disclosed
US-20240124413-A1 COMPOUNDS AND COMPOSITIONS FOR USE IN TREATING SKIN DISORDERS KAMARI PHARMA LTD. (IL) 2024-04-18 US disclosed
US-11807621-B2 Compounds and compositions for use in treating skin disorders KAMARI PHARMA LTD. (IL) 2023-11-07 US disclosed
EP-4096661-A1 COMPOUNDS AND COMPOSITIONS FOR USE IN TREATING SKIN DISORDERS Kamari Pharma Ltd. (IL) 2022-12-07 EP disclosed
CN-115335050-A Compounds and compositions for treating skin conditions 卡玛瑞制药有限公司 2022-11-11 CN disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
US-20220332697-A1 COMPOUNDS AND COMPOSITIONS FOR USE IN TREATING SKIN DISORDERS KAMARI PHARMA LTD. (IL) 2022-10-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12435061-B2 Compounds and compositions for use in treating skin disorders RDX, HAX1, F12 CCR1 761/4885ALDH1A1 629/4885ERN1 3617/4885
US-20240124413-A1 COMPOUNDS AND COMPOSITIONS FOR USE IN TREATING SKIN DISORDERS RDX, HAX1, F12 CCR1 761/4885ALDH1A1 629/4885ERN1 3617/4885
US-11807621-B2 Compounds and compositions for use in treating skin disorders RDX, HAX1, F12 CCR1 761/4885ALDH1A1 629/4885ERN1 3617/4885
US-20220332697-A1 COMPOUNDS AND COMPOSITIONS FOR USE IN TREATING SKIN DISORDERS RDX, HAX1, F12 CCR1 761/4885ALDH1A1 629/4885ERN1 3617/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.