Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 17/20 | 0.83 |
| ▸ | NR1I2 | O75469 | 4/20 | 0.72 |
| ▸ | RORA | P35398 | 4/20 | 0.72 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.72 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.72 |
| ▸ | RORB | Q92753 | 4/20 | 0.72 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.72 |
| ▸ | CPT2 | P23786 | 1/20 | 0.61 |
| ▸ | CPT1A | P50416 | 1/20 | 0.61 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28843031 | 1.00 | RORC (0.83) | RORCNR1I2RORANR1H2NR1H3 | |
| SCHEMBL5023200 | 0.88 | RORC (0.84) | RORCNR1I2RORANR1H2NR1H3 | |
| SCHEMBL5022112 | 0.88 | RORC (0.80) | RORCNR1I2RORANR1H2NR1H3 | |
| SCHEMBL15628988 | 0.86 | RORC (0.80) | RORCNR1I2RORANR1H2NR1H3 | |
| SCHEMBL15628996 | 0.84 | RORC (0.86) | RORCNR1I2RORANR1H2NR1H3 | |
| SCHEMBL5023206 | 0.84 | RORC (1.00) | RORCNR1I2RORANR1H2NR1H3 | |
| SCHEMBL15628911 | 0.84 | RORC (0.80) | RORCNR1I2RORANR1H2NR1H3 | |
| SCHEMBL5021848 | 0.83 | RORC (0.87) | RORCNR1I2RORANR1H2NR1H3 | |
| SCHEMBL5023460 | 0.83 | RORC (0.83) | RORCNR1I2RORANR1H2NR1H3 | |
| SCHEMBL18359198 | 0.83 | RORC (0.83) | RORCNR1I2RORANR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107021923-B | Tetrahydroquinoline related bicyclic compound and application thereof | 中国科学院广州生物医药与健康研究院 | 2022-09-23 | — | — | CN | disclosed |