SCHEMBL29935468

SCHEMBL29935468

O=C(NC(Cc1c[nH]c2ccccc12)C(=O)O)OCc1ccccc1

nearest known ligand 0.76

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NMBR P28336 2/20 0.76
MAPT P10636 2/20 0.71
GAA P10253 1/20 0.71
HTT P42858 1/20 0.71
LMNA P02545 1/20 0.69
ECE1 P42892 4/20 0.69
MME P08473 3/20 0.69
ACE P12821 2/20 0.65
CASP1 P29466 1/20 0.64
SSTR1 P30872 1/20 0.63
ALOX15 P16050 1/20 0.63
LNPEP Q9UIQ6 1/20 0.63
CA2 P00918 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29401760 1.00 NMBR (0.76) NMBRMAPTGAAHTTLMNA
SCHEMBL29386277 1.00 NMBR (0.76) NMBRMAPTGAAHTTLMNA
SCHEMBL1285921 1.00 NMBR (0.76) NMBRMAPTGAAHTTLMNA
SCHEMBL220800 1.00 NMBR (0.76) NMBRMAPTGAAHTTLMNA
SCHEMBL3808330 1.00 NMBR (0.76) NMBRMAPTGAAHTTLMNA
SCHEMBL14595066 0.96 NMBR (0.76) NMBRMAPTGAAHTTLMNA
SCHEMBL5403959 0.94 MME (0.69) NMBRMAPTGAAHTTLMNA
SCHEMBL31326046 0.94 NMBR (0.74) NMBRMAPTGAAHTTLMNA
SCHEMBL29401161 0.93 NMBR (0.76) NMBRMAPTGAAHTTLMNA
SCHEMBL3265534 0.93 NMBR (0.76) NMBRMAPTGAAHTTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 EP claimed
WO-2024167565-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS PURDUE RESEARCH FOUNDATION (US) 2024-08-15 WO claimed
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 EP disclosed
WO-2024167565-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS PURDUE RESEARCH FOUNDATION (US) 2024-08-15 WO disclosed
EP-4073242-A1 COMPOSITIONS AND METHODS FOR POTENTIATING IMMUNE ACTIVITY Kumquat Biosciences Inc. (US) 2022-10-19 EP disclosed