Sugi Predict

Sugi Predict / Compounds / SCHEMBL220800

SCHEMBL220800

SCHEMBL220800

O=C(N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O)OCc1ccccc1

nearest known ligand 0.76

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ NMBR P28336 2/20 0.76
▸ MAPT P10636 2/20 0.71
▸ GAA P10253 1/20 0.71
▸ HTT P42858 1/20 0.71
▸ LMNA P02545 1/20 0.69
▸ ECE1 P42892 4/20 0.69
▸ MME P08473 3/20 0.69
▸ ACE P12821 2/20 0.65
▸ CASP1 P29466 1/20 0.64
▸ SSTR1 P30872 1/20 0.63
▸ ALOX15 P16050 1/20 0.63
▸ LNPEP Q9UIQ6 1/20 0.63
▸ CA2 P00918 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29401760 1.00 NMBR (0.76) NMBRMAPTGAAHTTLMNA
SCHEMBL29386277 1.00 NMBR (0.76) NMBRMAPTGAAHTTLMNA
SCHEMBL1285921 1.00 NMBR (0.76) NMBRMAPTGAAHTTLMNA
SCHEMBL29935468 1.00 NMBR (0.76) NMBRMAPTGAAHTTLMNA
SCHEMBL3808330 1.00 NMBR (0.76) NMBRMAPTGAAHTTLMNA
SCHEMBL14595066 0.96 NMBR (0.76) NMBRMAPTGAAHTTLMNA
SCHEMBL5403959 0.94 MME (0.69) NMBRMAPTGAAHTTLMNA
SCHEMBL31326046 0.94 NMBR (0.74) NMBRMAPTGAAHTTLMNA
SCHEMBL29401161 0.93 NMBR (0.76) NMBRMAPTGAAHTTLMNA
SCHEMBL3265534 0.93 NMBR (0.76) NMBRMAPTGAAHTTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 194 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116726241-B Collagen hemostatic and antibacterial dressing and preparation method thereof 江苏亨瑞生物医药科技有限公司 2023-10-20 — — CN claimed
US-20230295086-A1 NOVEL PSILOCIN DERIVATIVES HAVING PRODRUG PROPERTIES HERCULES CAPITAL, INC. 2023-09-21 — — US claimed
CN-116726241-A Collagen hemostatic and antibacterial dressing and preparation method thereof 江苏亨瑞生物医药科技有限公司 2023-09-12 — — CN claimed
EP-4200279-A1 NOVEL PSILOCIN DERIVATIVES HAVING PRODRUG PROPERTIES COMPASS Pathfinder Limited (GB) 2023-06-28 — — EP claimed
CN-116075499-A Novel dephosphorylated galectin derivatives with prodrug properties 指南针探路者有限公司 2023-05-05 — — CN claimed
WO-2022038299-A1 NOVEL PSILOCIN DERIVATIVES HAVING PRODRUG PROPERTIES COMPASS PATHFINDER LIMITED (GB) 2022-02-24 — — WO claimed
US-20100068197-A1 PHARMACEUTICAL COMPOUNDS AS INHIBITORS OF CELL PROLIFERATION AND THE USE THEREOF MYRIAD PHARMACEUTICALS, INC. (US) 2010-03-18 — — US claimed
US-4283337-A Process for the purification of tryptophane and derivatives of tryptophane DEUTSCHE GOLD UND- SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) 1981-08-11 — — US claimed
US-4085207-A AND AT LEAST ONE OF N-ACYL-L-TRYPTOPHANS AND N-ACYL-L-PROLINES OTSUKA PHARMACEUTICAL FACTORY, INC. (JA) 1978-04-18 — — US claimed
CN-122059928-A Bifunctional chelators, PSMA ligand compounds, radiolabeled compounds and uses thereof 广州医科大学附属第一医院（广州呼吸中心） 2026-05-19 — — CN disclosed
US-20260125390-A1 SOLID FORMS OF MACROCYCLIC COMPOUNDS, SALTS AND FORMULATIONS THEREOF, AND METHODS OF PREPARING AND USING THE SAME KURA ONCOLOGY INC (US) 2026-05-07 — — US disclosed
EP-4720073-A1 SOLID FORMS OF A MACROCYCLIC FARNESYLTRANSFERASE INHIBITOR AND FORMULATIONS THEREOF, AND METHODS OF PREPARING AND USING THE MACROCYCLIC COMPOUND AND ITS SOLID FORMS Kura Oncology, Inc. (US) 2026-04-08 — — EP disclosed
US-12466835-B1 Solid forms of macrocyclic compounds, salts and formulations thereof, and methods of preparing and using the same KURA ONCOLOGY, INC. (US) 2025-11-11 — — US disclosed
US-20250296915-A1 NOVEL AMINO ACID DERIVATIVES PEPTIDREAM INC (JP) 2025-09-25 — — US disclosed
US-4100274-A LULIBERIN ANTAGONIST IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1978-07-11 — — US disclosed
US-4085207-A AND AT LEAST ONE OF N-ACYL-L-TRYPTOPHANS AND N-ACYL-L-PROLINES OTSUKA PHARMACEUTICAL FACTORY, INC. (JA) 1978-04-18 — — US disclosed
US-4000297-A GASTROENTERIC ACTIVITY ROTTA RESEARCH LABORATORIUM S.P.A. (IT) 1976-12-28 — — US disclosed
US-3976635-A Novel esterifying agents, and their production and use FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1976-08-24 — — US disclosed
US-3936452-A Process of producing pyrimidyl thiocarbonates NITTO BOSEKI CO., LTD. (JA) 1976-02-03 — — US disclosed
US-3932375-A PROTECTING GROUPS NITTO BOSEKI CO. LTD. (JA) 1976-01-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260125390-A1 SOLID FORMS OF MACROCYCLIC COMPOUNDS, SALTS AND FORMULATIONS THEREOF, AND METHODS OF PREPARING AND USING THE SAME FDPS, PCTP, MTTP NMBR 4070/4885MAPT 2019/4885GAA 2995/4885
US-12466835-B1 Solid forms of macrocyclic compounds, salts and formulations thereof, and methods of preparing and using the same FNTA, SF3B1, SF3A1 NMBR 4108/4885MAPT 2911/4885GAA 3779/4885
US-20230295086-A1 NOVEL PSILOCIN DERIVATIVES HAVING PRODRUG PROPERTIES HTR2A, HTR2C, HTR5A NMBR 779/4885MAPT 2299/4885GAA 1522/4885
US-20250296915-A1 NOVEL AMINO ACID DERIVATIVES DNPEP, BCAT1, ANPEP NMBR 1269/4885MAPT 2072/4885GAA 1994/4885
US-20100068197-A1 PHARMACEUTICAL COMPOUNDS AS INHIBITORS OF CELL PROLIFERATION AND THE USE THEREOF MKI67, CCNI, CCNA1 NMBR 2560/4885MAPT 3821/4885GAA 120/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.