SCHEMBL29935481

SCHEMBL29935481

CCCCOC(=O)N(CCOC)Cc1ccc(-c2cc3nccc(Cl)c3s2)nc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MST1R Q04912 8/20 0.43
SRC P12931 2/20 0.37
KDR P35968 3/20 0.36
MET P08581 2/20 0.36
AXL P30530 2/20 0.36
FLT3 P36888 2/20 0.36
NTRK1 P04629 1/20 0.36
KIT P10721 1/20 0.36
NTRK2 Q16620 1/20 0.36
PLK4 O00444 1/20 0.35
MAP4K4 O95819 1/20 0.35
ABL1 P00519 1/20 0.35
LCK P06239 1/20 0.35
FYN P06241 1/20 0.35
LYN P07948 1/20 0.35
HCK P08631 1/20 0.35
PDGFRB P09619 1/20 0.35
BCR P11274 1/20 0.35
ABL2 P42684 1/20 0.35
FRK P42685 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL107493 0.87 MST1R (0.42) MST1RSRCKDRMETAXL
SCHEMBL14839819 0.87 MST1R (0.42) MST1RSRCKDRMETAXL
SCHEMBL171880 0.87 MST1R (0.53) MST1RSRCKDRMETAXL
SCHEMBL29802582 0.87 MST1R (0.53) MST1RSRCKDRMETAXL
SCHEMBL2602337 0.81 MST1R (0.46) MST1RSRCKDRMETAXL
SCHEMBL2533156 0.79 MST1R (0.46) MST1RSRCKDRMETAXL
SCHEMBL19027011 0.78 MST1R (0.42) MST1RSRCKDRMETAXL
SCHEMBL2121545 0.77 MTOR (0.35) MST1RSRCKDRMETAXL
SCHEMBL23071633 0.74 MET (0.43) MST1RSRCKDRMETAXL
SCHEMBL12229310 0.74 MST1R (0.40) MST1RSRCKDRMETAXL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220288043-A1 THIENOPYRIDINE DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING SAME WELLMARKER BIO CO, LTD. (KR) 2022-09-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220288043-A1 THIENOPYRIDINE DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING SAME PRKACA, MAP4K5, MAPKAPK5 MST1R 1943/4885SRC 289/4885KDR 3460/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.