Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 7/20 | 0.66 |
| ▸ | PLG | P00747 | 4/20 | 0.66 |
| ▸ | PLAT | P00750 | 4/20 | 0.66 |
| ▸ | CNR1 | P21554 | 1/20 | 0.62 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 4/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | STAT1 | P42224 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30209664 | 0.90 | PLAU (0.66) | PLAUPLGPLATCNR1TRPV1 | |
| SCHEMBL29936402 | 0.89 | PLAU (0.65) | PLAUPLGPLATCNR1TRPV1 | |
| SCHEMBL29936541 | 0.87 | PLAU (0.65) | PLAUPLGPLATCNR1TRPV1 | |
| SCHEMBL29936190 | 0.87 | KMT2A (0.67) | PLAUPLGPLATCNR1TRPV1 | |
| SCHEMBL5943974 | 0.81 | TRPV1 (0.70) | PLAUPLGPLATCNR1TRPV1 | |
| SCHEMBL5944122 | 0.79 | TRPV1 (0.63) | PLAUPLGPLATTRPV1KMT2A | |
| SCHEMBL25308207 | 0.77 | MAPT (0.60) | PLAUPLGPLATCNR1RAB9A | |
| SCHEMBL31115046 | 0.76 | KMT2A (0.64) | PLAUPLGPLATTRPV1RAB9A | |
| SCHEMBL20557353 | 0.76 | CNR1 (1.00) | CNR1TP53TSHR | |
| SCHEMBL30469241 | 0.76 | CNR1 (1.00) | CNR1TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116478070-B | Compound, pharmaceutical composition and application thereof in field of vasodilation or antiviral | 山东第一医科大学(山东省医学科学院) | 2024-09-27 | — | — | CN | claimed |
| CN-116478070-A | Compound, pharmaceutical composition and application thereof in field of vasodilation or antiviral | 山东第一医科大学(山东省医学科学院) | 2023-07-25 | — | — | CN | claimed |
| CN-115093359-A | Compound, pharmaceutical composition and application of compound and pharmaceutical composition in field of blood vessel expansion or virus resistance | 山东第一医科大学(山东省医学科学院) | 2022-09-23 | — | — | CN | claimed |
| CN-116478070-B | Compound, pharmaceutical composition and application thereof in field of vasodilation or antiviral | 山东第一医科大学(山东省医学科学院) | 2024-09-27 | — | — | CN | disclosed |
| CN-116478070-A | Compound, pharmaceutical composition and application thereof in field of vasodilation or antiviral | 山东第一医科大学(山东省医学科学院) | 2023-07-25 | — | — | CN | disclosed |
| CN-115093359-B | Compound, pharmaceutical composition and application thereof in field of vasodilation or antiviral | 山东第一医科大学(山东省医学科学院) | 2023-06-09 | — | — | CN | disclosed |
| CN-115093359-A | Compound, pharmaceutical composition and application of compound and pharmaceutical composition in field of blood vessel expansion or virus resistance | 山东第一医科大学(山东省医学科学院) | 2022-09-23 | — | — | CN | disclosed |