Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 17/20 | 1.00 |
| ▸ | TLR9 | Q9NR96 | 15/20 | 1.00 |
| ▸ | SPIN1 | Q9Y657 | 3/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19385134 | 1.00 | TLR7 (1.00) | TLR7TLR9SPIN1 | |
| SCHEMBL19405196 | 0.90 | TLR7 (1.00) | TLR7TLR9SPIN1 | |
| SCHEMBL19406427 | 0.89 | TLR7 (0.80) | TLR7TLR9SPIN1 | |
| SCHEMBL19406367 | 0.85 | TLR7 (0.82) | TLR7TLR9SPIN1 | |
| SCHEMBL19405214 | 0.85 | TLR7 (1.00) | TLR7TLR9SPIN1 | |
| SCHEMBL19385084 | 0.84 | TLR7 (1.00) | TLR7TLR9SPIN1 | |
| SCHEMBL19385172 | 0.84 | TLR7 (1.00) | TLR7TLR9SPIN1 | |
| SCHEMBL25207922 | 0.83 | TLR7 (0.71) | TLR7TLR9SPIN1 | |
| SCHEMBL29385899 | 0.83 | TLR7 (0.71) | TLR7TLR9SPIN1 | |
| SCHEMBL15667852 | 0.83 | TLR9 (0.71) | TLR7TLR9SPIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3433249-B1 | BLOCKING TOLL-LIKE RECEPTOR 9 SIGNALING WITH SMALL MOLECULE ANTAGONIST | COUNCIL SCIENT IND RES (IN) | 2022-11-09 | — | — | EP | disclosed |