Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 18/20 | 1.00 |
| ▸ | TLR9 | Q9NR96 | 16/20 | 1.00 |
| ▸ | SPIN1 | Q9Y657 | 2/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29936638 | 0.90 | TLR7 (1.00) | TLR7TLR9SPIN1 | |
| SCHEMBL19385134 | 0.90 | TLR7 (1.00) | TLR7TLR9SPIN1 | |
| SCHEMBL19406433 | 0.90 | TLR7 (0.81) | TLR7TLR9 | |
| SCHEMBL19406367 | 0.89 | TLR7 (0.82) | TLR7TLR9SPIN1 | |
| SCHEMBL19405214 | 0.89 | TLR7 (1.00) | TLR7TLR9SPIN1 | |
| SCHEMBL19385084 | 0.88 | TLR7 (1.00) | TLR7TLR9SPIN1 | |
| SCHEMBL19385172 | 0.87 | TLR7 (1.00) | TLR7TLR9SPIN1 | |
| SCHEMBL19385355 | 0.86 | TLR7 (1.00) | TLR7TLR9SPIN1 | |
| SCHEMBL19385052 | 0.85 | TLR7 (1.00) | TLR7TLR9SPIN1 | |
| SCHEMBL19385235 | 0.85 | TLR9 (0.77) | TLR7TLR9SPIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017163264-A1 | BLOCKING TOLL-LIKE RECEPTOR 9 SIGNALING WITH SMALL MOLECULE ANTAGONIST | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-09-28 | — | — | WO | disclosed |