Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.60 |
| ▸ | FTO | Q9C0B1 | 8/20 | 0.55 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.53 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.51 |
| ▸ | MIF | P14174 | 1/20 | 0.49 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.49 |
| ▸ | NQO1 | P15559 | 1/20 | 0.49 |
| ▸ | RORC | P51449 | 1/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.48 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26430106 | 0.88 | TTR (0.61) | TTRFTOKEAP1NAALAD2MIF | |
| SCHEMBL15298976 | 0.88 | TTR (0.60) | TTRFTOKEAP1NAALAD2MIF | |
| SCHEMBL23417780 | 0.88 | TTR (0.64) | TTRFTOKEAP1NAALAD2MIF | |
| SCHEMBL31542972 | 0.88 | TTR (0.64) | TTRFTOKEAP1NAALAD2MIF | |
| SCHEMBL31542969 | 0.88 | TTR (0.64) | TTRFTOKEAP1NAALAD2MIF | |
| SCHEMBL27016019 | 0.87 | TTR (0.64) | TTRFTOKEAP1NAALAD2MIF | |
| SCHEMBL23417940 | 0.86 | TTR (0.63) | TTRFTOKEAP1NAALAD2MIF | |
| SCHEMBL31085457 | 0.86 | TTR (0.58) | TTRFTOKEAP1NAALAD2MIF | |
| SCHEMBL22542526 | 0.85 | TTR (0.56) | TTRFTOKEAP1NAALAD2MIF | |
| SCHEMBL24335633 | 0.85 | TTR (0.54) | TTRFTOKEAP1NAALAD2MIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115335370-A | Fibroblast activation protein ligands for targeted delivery applications | 菲洛谢姆股份公司 | 2022-11-11 | — | — | CN | disclosed |