Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 13/20 | 0.74 |
| ▸ | NPC1 | O15118 | 12/20 | 0.74 |
| ▸ | MAPT | P10636 | 10/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.74 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.74 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.74 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.74 |
| ▸ | HPGD | P15428 | 4/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.61 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.61 |
| ▸ | RELA | Q04206 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | TPH1 | P17752 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16592531 | 1.00 | RAB9A (0.74) | RAB9ANPC1MAPTSMN1; SMN2NR1H4 | |
| SCHEMBL6697420 | 0.85 | NR1H4 (1.00) | RAB9ANPC1MAPTSMN1; SMN2NR1H4 | |
| SCHEMBL7291752 | 0.85 | NR1H4 (1.00) | RAB9ANPC1MAPTSMN1; SMN2NR1H4 | |
| SCHEMBL12895918 | 0.85 | RAB9A (0.76) | RAB9ANPC1MAPTSMN1; SMN2NR1H4 | |
| SCHEMBL13416230 | 0.84 | NPC1 (1.00) | RAB9ANPC1MAPTSMN1; SMN2NR1H4 | |
| SCHEMBL3057492 | 0.84 | RAB9A (0.74) | RAB9ANPC1MAPTSMN1; SMN2NR1H4 | |
| SCHEMBL26095707 | 0.84 | RAB9A (1.00) | RAB9ANPC1MAPTSMN1; SMN2NR1H4 | |
| SCHEMBL3057134 | 0.84 | RAB9A (0.74) | RAB9ANPC1MAPTSMN1; SMN2NR1H4 | |
| SCHEMBL16769354 | 0.83 | NPC1 (0.68) | RAB9ANPC1MAPTSMN1; SMN2NR1H4 | |
| SCHEMBL16592612 | 0.83 | RAB9A (0.72) | RAB9ANPC1MAPTSMN1; SMN2NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4304630-A1 | SMALL MOLECULE ANTAGONISTS FOR THE RELAXIN-3/RXFP3 SYSTEM | Research Triangle Institute (US) | 2024-01-17 | — | — | EP | disclosed |
| WO-2022192126-A1 | SMALL MOLECULE ANTAGONISTS FOR THE RELAXIN-3/RXFP3 SYSTEM | RESEARCH TRIANGLE INSTITUTE (US) | 2022-09-15 | — | — | WO | disclosed |