Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.78 |
| ▸ | RNASEL | Q05823 | 4/20 | 0.65 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.64 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.64 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.60 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.60 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | CA4 | P22748 | 1/20 | 0.59 |
| ▸ | CA9 | Q16790 | 1/20 | 0.59 |
| ▸ | CA5A | P35218 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | NT5E | P21589 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | HINT1 | P49773 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8622533 | 1.00 | ADORA3 (0.78) | ADORA3RNASELADORA2AADORA2BDNMT1 | |
| SCHEMBL4454099 | 0.90 | ADORA3 (0.80) | ADORA3ADORA2AADORA2BADORA1CA1 | |
| SCHEMBL1938203 | 0.90 | ADORA3 (0.80) | ADORA3ADORA2AADORA2BADORA1CA1 | |
| SCHEMBL12443734 | 0.90 | ADORA3 (0.80) | ADORA3ADORA2AADORA2BADORA1CA1 | |
| SCHEMBL13524754 | 0.88 | ADORA3 (0.77) | ADORA3ADORA2AADORA2BDNMT1DNMT3B | |
| SCHEMBL4457018 | 0.88 | ADORA3 (0.77) | ADORA3ADORA2AADORA2BDNMT1DNMT3B | |
| SCHEMBL4451649 | 0.88 | ADORA3 (1.00) | ADORA3ADORA2AADORA2BADORA1CA1 | |
| SCHEMBL4451640 | 0.88 | ADORA3 (1.00) | ADORA3ADORA2AADORA2BADORA1CA1 | |
| SCHEMBL4457021 | 0.88 | ADORA3 (0.77) | ADORA3ADORA2AADORA2BDNMT1DNMT3B | |
| SCHEMBL10459402 | 0.88 | ADORA3 (0.77) | ADORA3ADORA2AADORA2BDNMT1ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3212201-B1 | NUCLEOSIDE KINASE INHIBITORS | BCI PHARMA (FR) | 2022-10-19 | — | — | EP | claimed |