Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK2 | Q92630 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 18/20 | 0.37 |
| ▸ | CDK1 | P06493 | 5/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.37 |
| ▸ | CCND1 | P24385 | 2/20 | 0.37 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22650831 | 0.84 | CDK4 (0.41) | CDK4CDK1CCNB1CCND1CDK6 | |
| SCHEMBL31589956 | 0.83 | CDK4 (0.38) | DYRK2CDK4CDK1CCNB1CCND1 | |
| SCHEMBL29491149 | 0.83 | CDK4 (0.38) | DYRK2CDK4CDK1CCNB1CCND1 | |
| SCHEMBL22650838 | 0.83 | CDK4 (0.41) | CDK4CDK1CCNB1CCND1CDK6 | |
| SCHEMBL22650837 | 0.83 | CDK4 (0.41) | CDK4CDK1CCNB1CCND1CDK6 | |
| SCHEMBL22650835 | 0.83 | CDK4 (0.41) | CDK4CDK1CCNB1CCND1CDK6 | |
| SCHEMBL29491156 | 0.83 | CDK4 (0.41) | CDK4CDK1CCNB1CCND1CDK6 | |
| SCHEMBL31590654 | 0.82 | DYRK2 (0.42) | DYRK2CDK4CDK1CCNB1CCND1 | |
| SCHEMBL29936584 | 0.82 | DYRK2 (0.42) | DYRK2CDK4CDK1CCNB1CCND1 | |
| SCHEMBL22650594 | 0.82 | CDK4 (0.42) | DYRK2CDK4CDK1CCNB1CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220296595-A1 | CDK INHIBITORS | GENENTECH, INC. | 2022-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220296595-A1 | CDK INHIBITORS | CDKL1, CDK9, CDK6 | DYRK2 869/4885CDK4 10/4885CDK1 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.