Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.84 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.60 |
| ▸ | EML4 | Q9HC35 | 2/20 | 0.59 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.57 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24663098 | 1.00 | EGFR (0.84) | EGFRALKEML4ERBB3PTK2 | |
| SCHEMBL29936744 | 0.93 | EGFR (0.74) | EGFRALKEML4ERBB3PTK2 | |
| SCHEMBL24662609 | 0.93 | EGFR (0.74) | EGFRALKEML4ERBB3PTK2 | |
| SCHEMBL27004241 | 0.91 | EGFR (0.71) | EGFRALKEML4ERBB3PTK2 | |
| SCHEMBL24663149 | 0.86 | EGFR (0.81) | EGFRALKEML4PTK2KCNH2 | |
| SCHEMBL30717902 | 0.86 | EGFR (0.81) | EGFRALKEML4PTK2KCNH2 | |
| SCHEMBL24663107 | 0.86 | EGFR (0.80) | EGFRALKEML4PTK2KCNH2 | |
| SCHEMBL27001636 | 0.85 | EGFR (0.79) | EGFRALKEML4PTK2 | |
| SCHEMBL29936474 | 0.85 | EGFR (0.79) | EGFRALKEML4PTK2 | |
| SCHEMBL22819201 | 0.83 | EGFR (0.65) | EGFRALKEML4ERBB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022191664-A1 | NOVEL PYRIMIDINE DERIVATIVE SHOWING INHIBITION EFFECT ON GROWTH OF CANCER CELLS | 주식회사 온코빅스 | 2022-09-15 | — | — | WO | claimed |
| EP-4306518-A1 | NOVEL PYRIMIDINE DERIVATIVE SHOWING INHIBITION EFFECT ON GROWTH OF CANCER CELLS | Oncobix Co., Ltd. (KR) | 2024-01-17 | — | — | EP | disclosed |
| WO-2022191664-A1 | NOVEL PYRIMIDINE DERIVATIVE SHOWING INHIBITION EFFECT ON GROWTH OF CANCER CELLS | 주식회사 온코빅스 | 2022-09-15 | — | — | WO | disclosed |