Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.65 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.62 |
| ▸ | EML4 | Q9HC35 | 2/20 | 0.61 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22806784 | 0.89 | EGFR (0.65) | EGFRALKEML4ERBB3 | |
| Phosphine SCHEMBL22806798 | 0.89 | EGFR (0.64) | EGFRALKEML4ERBB3 | |
| SCHEMBL22819312 | 0.85 | EGFR (0.78) | EGFRALKEML4 | |
| SCHEMBL35210347 | 0.84 | EGFR (0.61) | EGFRALKEML4 | |
| SCHEMBL19089670 | 0.84 | EGFR (0.61) | EGFRALKEML4 | |
| SCHEMBL35210286 | 0.84 | EGFR (0.61) | EGFRALKEML4 | |
| SCHEMBL20548806 | 0.84 | EGFR (0.61) | EGFRALKEML4 | |
| SCHEMBL24662635 | 0.83 | EGFR (0.83) | EGFRALKEML4ERBB3 | |
| SCHEMBL24663098 | 0.83 | EGFR (0.84) | EGFRALKEML4ERBB3 | |
| SCHEMBL29936740 | 0.83 | EGFR (0.84) | EGFRALKEML4ERBB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020256477-A1 | PYRIMIDINE DERIVATIVE INHIBITING GROWTH OF CANCER CELL AND MEDICINAL USE THEREOF | 주식회사 온코빅스 | 2020-12-24 | — | — | WO | disclosed |