Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 11/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24663094 | 1.00 | EGFR (0.50) | EGFRMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL29936610 | 0.86 | EGFR (0.51) | EGFRALDH1A1CDK4CDK2ALK | |
| SCHEMBL24662651 | 0.86 | EGFR (0.51) | EGFRALDH1A1CDK4CDK2ALK | |
| SCHEMBL29936744 | 0.82 | EGFR (0.74) | EGFRALK | |
| SCHEMBL24662609 | 0.82 | EGFR (0.74) | EGFRALK | |
| SCHEMBL24663062 | 0.82 | ALDH1A1 (0.49) | EGFRMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL30669956 | 0.82 | ALDH1A1 (0.49) | EGFRMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL24662666 | 0.80 | CDK4 (0.37) | EGFRMEN1KMT2AMAPTCDK4 | |
| SCHEMBL27004238 | 0.77 | EGFR (0.44) | EGFRALDH1A1ALK | |
| SCHEMBL22819311 | 0.76 | CDK4 (0.42) | EGFRMEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4306518-A1 | NOVEL PYRIMIDINE DERIVATIVE SHOWING INHIBITION EFFECT ON GROWTH OF CANCER CELLS | Oncobix Co., Ltd. (KR) | 2024-01-17 | — | — | EP | disclosed |
| WO-2022191664-A1 | NOVEL PYRIMIDINE DERIVATIVE SHOWING INHIBITION EFFECT ON GROWTH OF CANCER CELLS | 주식회사 온코빅스 | 2022-09-15 | — | — | WO | disclosed |