SCHEMBL29937064

CC(C)C[C@H](NC(=O)[C@H](CS)NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 6)

	gene	UniProt	supporting neighbours	confidence
▸	PTPN1	P18031	7/20	0.47

▸	MDM4	O15151	2/20	0.43

▸	TP53	P04637	2/20	0.43

▸	MDM2	Q00987	2/20	0.41

▸	MME	P08473	1/20	0.41

▸	FDFT1	P37268	1/20	0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29937114	1.00	PTPN1 (0.47)	PTPN1MDM4TP53MDM2MME
SCHEMBL29937002	0.96	PTPN1 (0.50)	PTPN1MDM4TP53MDM2
SCHEMBL29936762	0.96	PTPN1 (0.50)	PTPN1MDM4TP53MDM2
SCHEMBL29936857	0.96	PTPN1 (0.50)	PTPN1MDM4TP53MDM2
SCHEMBL29937039	0.96	PTPN1 (0.50)	PTPN1MDM4TP53MDM2
SCHEMBL30718996	0.95	PTPN1 (0.49)	PTPN1MDM4TP53MDM2
SCHEMBL30396468	0.95	PTPN1 (0.55)	PTPN1MDM4TP53MDM2FDFT1
SCHEMBL30397976	0.95	PTPN1 (0.55)	PTPN1MDM4TP53MDM2FDFT1
SCHEMBL30397179	0.95	PTPN1 (0.55)	PTPN1MDM4TP53MDM2FDFT1
SCHEMBL30241363	0.94	PTPN1 (0.50)	PTPN1MDM4TP53MDM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-115093458-A	Acid-activated cell-penetrating polypeptide carrier and application thereof	倪京满	2022-09-23	—	—	CN	disclosed