Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 8/20 | 0.55 |
| ▸ | GRB2 | P62993 | 1/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.40 |
| ▸ | MDM4 | O15151 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30396468 | 1.00 | PTPN1 (0.55) | PTPN1GRB2MDM2MDM4TP53 | |
| SCHEMBL30397976 | 1.00 | PTPN1 (0.55) | PTPN1GRB2MDM2MDM4TP53 | |
| SCHEMBL29937064 | 0.95 | PTPN1 (0.47) | PTPN1MDM2MDM4TP53FDFT1 | |
| SCHEMBL29937114 | 0.95 | PTPN1 (0.47) | PTPN1MDM2MDM4TP53FDFT1 | |
| SCHEMBL29936762 | 0.91 | PTPN1 (0.50) | PTPN1MDM2MDM4TP53 | |
| SCHEMBL29936857 | 0.91 | PTPN1 (0.50) | PTPN1MDM2MDM4TP53 | |
| SCHEMBL29937002 | 0.91 | PTPN1 (0.50) | PTPN1MDM2MDM4TP53 | |
| SCHEMBL29937039 | 0.91 | PTPN1 (0.50) | PTPN1MDM2MDM4TP53 | |
| SCHEMBL30718996 | 0.90 | PTPN1 (0.49) | PTPN1MDM2MDM4TP53 | |
| SCHEMBL30241363 | 0.90 | PTPN1 (0.50) | PTPN1MDM2MDM4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110862458-B | Combined peptide with acid activated antitumor activity and clinical application thereof | 倪京满 | 2023-05-05 | — | — | CN | disclosed |