SCHEMBL29937482

SCHEMBL29937482

CC(=O)NCc1cccc(Cl)c1

nearest known ligand 0.67

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.55
RAB9A P51151 1/20 0.55
RXFP1 Q9HBX9 1/20 0.55
APEX1 P27695 1/20 0.55
MEN1 O00255 1/20 0.52
HCRTR1 O43613 1/20 0.52
KMT2A Q03164 1/20 0.52
P2RX7 Q99572 1/20 0.52
HDAC1 Q13547 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL884912 1.00 NPC1 (0.55) NPC1RAB9ARXFP1APEX1MEN1
SCHEMBL1899410 0.87 NPSR1 (0.57) RAB9AMEN1KMT2AHDAC1
SCHEMBL3552958 0.84 RXFP1 (0.59) NPC1RAB9ARXFP1APEX1MEN1
SCHEMBL13647316 0.83 GAA (0.54) NPC1RAB9ARXFP1APEX1
SCHEMBL30259909 0.83 NPC1 (0.59) NPC1RAB9ARXFP1APEX1KMT2A
SCHEMBL6159150 0.83 SMN1; SMN2 (0.66) NPC1RAB9AMEN1KMT2A
SCHEMBL6361162 0.83 NPC1 (0.59) NPC1RAB9ARXFP1APEX1KMT2A
SCHEMBL19974889 0.82 ALDH1A1 (0.51) NPC1RAB9ARXFP1APEX1MEN1
SCHEMBL4588413 0.82 PLA2G1B (0.56) NPC1RAB9ARXFP1APEX1HDAC1
SCHEMBL626329 0.82 CYP2C9 (0.62) NPC1RAB9AMEN1HCRTR1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122036718-A ALK5 inhibitor and preparation method and application thereof 安炎达医药技术(广州)有限公司 2026-05-15 CN disclosed
CN-115557849-A Method for synthesizing imide compound under induction of NBS and water by visible light 西南大学 2023-01-03 CN disclosed
WO-2022226203-A1 PROTEASE INHIBITORS AND METHODS OF USE THE CLEVELAND CLINIC FOUNDATION (US) 2022-10-27 WO disclosed