Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.56 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | TERT | O14746 | 3/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.47 |
| ▸ | PPARG | P37231 | 3/20 | 0.47 |
| ▸ | PPARD | Q03181 | 3/20 | 0.47 |
| ▸ | PPARA | Q07869 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | FABP4 | P15090 | 2/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20718358 | 0.89 | EPHX1 (0.48) | TP53PPARDMAPT | |
| SCHEMBL24919992 | 0.89 | EPHX1 (0.48) | TP53PPARDMAPT | |
| SCHEMBL28935295 | 0.88 | CA1 (0.48) | TP53PPARDMAPT | |
| SCHEMBL4658583 | 0.88 | CA1 (0.47) | TP53PPARDMAPT | |
| SCHEMBL10800485 | 0.83 | FAAH (0.59) | FAAHSOAT1CYP1A2CYP2C19KMT2A | |
| SCHEMBL379106 | 0.83 | FAAH (0.59) | FAAHSOAT1CYP1A2CYP2C19KMT2A | |
| SCHEMBL6283769 | 0.83 | FAAH (0.59) | FAAHSOAT1CYP1A2CYP2C19KMT2A | |
| SCHEMBL9238140 | 0.83 | FAAH (0.59) | FAAHSOAT1CYP1A2CYP2C19KMT2A | |
| SCHEMBL20303229 | 0.83 | FAAH (0.59) | FAAHSOAT1CYP1A2CYP2C19KMT2A | |
| SCHEMBL376319 | 0.81 | FAAH (0.61) | FAAHSOAT1CYP1A2CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4061797-A1 | IONIZABLE LIPIDS AND NANOPARTICLE COMPOSITIONS THEREOF | Generation Bio Co. (US) | 2022-09-28 | — | — | EP | disclosed |