Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 12/20 | 0.67 |
| ▸ | MGAM | O43451 | 10/20 | 0.67 |
| ▸ | AMY1A | P0DUB6 | 10/20 | 0.67 |
| ▸ | SI | P14410 | 10/20 | 0.67 |
| ▸ | MGAM2 | Q2M2H8 | 10/20 | 0.67 |
| ▸ | RAB9A | P51151 | 7/20 | 0.67 |
| ▸ | NPC1 | O15118 | 5/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL361654 | 0.84 | GAA (0.73) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL29625506 | 0.84 | GAA (0.73) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL2070662 | 0.83 | GAA (0.67) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL1689837 | 0.83 | GAA (0.67) | GAAMGAMAMY1ASIMGAM2 | |
| Hydrochloric Acid SCHEMBL1371916 | 0.83 | GAA (0.71) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL11524883 | 0.83 | GAA (0.67) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL16286769 | 0.83 | GAA (0.67) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL17895674 | 0.80 | GAA (0.63) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL12093975 | 0.80 | GAA (1.00) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL20109729 | 0.80 | GAA (0.63) | GAAMGAMAMY1ASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022226203-A1 | PROTEASE INHIBITORS AND METHODS OF USE | THE CLEVELAND CLINIC FOUNDATION (US) | 2022-10-27 | — | — | WO | disclosed |