SCHEMBL2070662

SCHEMBL2070662

NC(=O)Cn1nnc2ccccc21

nearest known ligand 0.73

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ GAA P10253 11/20 0.67
▸ MGAM O43451 9/20 0.67
▸ AMY1A P0DUB6 9/20 0.67
▸ SI P14410 9/20 0.67
▸ MGAM2 Q2M2H8 9/20 0.67
▸ RAB9A P51151 7/20 0.67
▸ NPC1 O15118 5/20 0.60
▸ SMN1; SMN2 Q16637 3/20 0.60
▸ CYP2C9 P11712 1/20 0.60
▸ CYP2C19 P33261 1/20 0.60
▸ EGLN3 Q9H6Z9 1/20 0.59
▸ MEN1 O00255 1/20 0.58
▸ KMT2A Q03164 1/20 0.58
▸ HSD17B10 Q99714 1/20 0.58
▸ KDM4E B2RXH2 1/20 0.57
▸ MAPT P10636 1/20 0.57
▸ SLC9A1 P19634 1/20 0.56
▸ TP53 P04637 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29625506 0.84 GAA (0.73) GAAMGAMAMY1ASIMGAM2
SCHEMBL361654 0.84 GAA (0.73) GAAMGAMAMY1ASIMGAM2
Hydrochloric Acid SCHEMBL1371916 0.83 GAA (0.71) GAAMGAMAMY1ASIMGAM2
SCHEMBL29937880 0.83 GAA (0.67) GAAMGAMAMY1ASIMGAM2
SCHEMBL1689837 0.83 GAA (0.67) GAAMGAMAMY1ASIMGAM2
SCHEMBL16286769 0.83 GAA (0.67) GAAMGAMAMY1ASIMGAM2
SCHEMBL11524883 0.83 GAA (0.67) GAAMGAMAMY1ASIMGAM2
SCHEMBL6846939 0.82 EGLN3 (0.68) GAAMGAMAMY1ASIMGAM2
SCHEMBL14526175 0.81 RAB9A (0.60) GAAMGAMAMY1ASIMGAM2
SCHEMBL17895674 0.80 GAA (0.63) GAAMGAMAMY1ASIMGAM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113589662-B Composition, stripping liquid, application of stripping liquid in stripping of photoresist or photoresist residues and stripping method 浙江奥首材料科技有限公司 2022-07-12 — — CN claimed
CN-113589662-A Composition, stripping liquid, application of stripping liquid in stripping of photoresist or photoresist residues and stripping method 浙江奥首材料科技有限公司 2021-11-02 — — CN claimed
US-8071764-B2 Compounds of reverse turn mimetics and the use thereof (2) CHOONGWAE PHARMA CORPORATION (KR) 2011-12-06 — — US claimed
US-20100228027-A1 NOVEL COMPOUNDS OF REVERSE TURN MIMETICS AND THE USE THEREOF (2) CHOONGWAE PHARMA CORPORATION (KR) 2010-09-09 — — US claimed
EP-2212328-A2 NOVEL COMPOUNDS OF REVERSE TURN MIMETICS AND THE USE THEREOF (2) Choongwae Pharma Corporation (KR) 2010-08-04 — — EP claimed
WO-2009051398-A2 NOVEL COMPOUNDS OF REVERSE TURN MIMETICS AND THE USE THEREOF (2) CHOONGWAE PHARMA CORPORATION (KR) 2009-04-23 — — WO claimed
CN-113589662-B Composition, stripping liquid, application of stripping liquid in stripping of photoresist or photoresist residues and stripping method 浙江奥首材料科技有限公司 2022-07-12 — — CN disclosed
CN-113589662-A Composition, stripping liquid, application of stripping liquid in stripping of photoresist or photoresist residues and stripping method 浙江奥首材料科技有限公司 2021-11-02 — — CN disclosed
CN-109535158-B Bisaryl maleimide compound and pharmaceutically acceptable salt thereof, and preparation method and application thereof 浙江工业大学 2021-04-23 — — CN disclosed
EP-2212328-B1 NOVEL COMPOUNDS OF REVERSE TURN MIMETICS AND THE USE THEREOF CHOONGWAE PHARMA CORP (KR) 2017-01-25 — — EP disclosed
US-20130289083-A1 IDO Inhibitors NEWLINK GENETICS CORPORATION 2013-10-31 — — US disclosed
US-20130289083-A1 IDO Inhibitors NEWLINK GENETICS CORPORATION 2013-10-31 — — US disclosed
EP-2635275-A1 GPR17-MODULATING COMPOUNDS, DIAGNOSTIC AND THERAPEUTIC USES THEREOF Centro Cardiologico Monzino SpA (IT) 2013-09-11 — — EP disclosed
US-20100144770-A1 Pyrimidinones as Casein Kinase II (CK2) Modulators EXELIXIS, INC. (US) 2010-06-10 — — US disclosed
EP-2074114-A1 PYRIMIDINONES AS CASEIN KINASE II (CK2) MODULATORS Exelixis, Inc. (US) 2009-07-01 — — EP disclosed
WO-2009051398-A2 NOVEL COMPOUNDS OF REVERSE TURN MIMETICS AND THE USE THEREOF (2) CHOONGWAE PHARMA CORPORATION (KR) 2009-04-23 — — WO disclosed
WO-2008143759-A1 PYRIMIDINONES AS CASEIN KINASE II (CK2) MODULATORS EXELIXIS, INC. (US) 2008-11-27 — — WO disclosed
US-20070072833-A1 Survivin inhibitors ABBVIE INC. 2007-03-29 — — US disclosed
US-4329454-A Cephalosporin compounds ELI LILLY AND COMPANY (US) 1982-05-11 — — US disclosed
US-4144391-A REPLACING AN ACETOXY GROUP BY A SULFUR NUCLEOPHILE ELI LILLY AND COMPANY (US) 1979-03-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070072833-A1 Survivin inhibitors XIAP, BIRC5, BIRC3 GAA 1540/4885MGAM 4761/4885AMY1A 4451/4885
US-20100228027-A1 NOVEL COMPOUNDS OF REVERSE TURN MIMETICS AND THE USE THEREOF (2) MCL1, BID, MYADM GAA 3527/4885MGAM 3549/4885AMY1A 4601/4885
US-20130289083-A1 IDO Inhibitors IDO1, IDO2, INMT GAA 1031/4885MGAM 369/4885AMY1A 3625/4885
US-20100144770-A1 Pyrimidinones as Casein Kinase II (CK2) Modulators CSNK2A1, CSNK2A2, CSNK1A1 GAA 1639/4885MGAM 3415/4885AMY1A 3500/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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