SCHEMBL29938019

SCHEMBL29938019

Nc1cc(/C=C/C2CCC(F)(F)CC2)cc2c1OCC2

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 1/20 0.32
TEAD2 Q15562 1/20 0.32
PARP1 P09874 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29149542 1.00 KDM1A (0.32) KDM1ATEAD2PARP1
SCHEMBL24750257 1.00 KDM1A (0.32) KDM1ATEAD2PARP1
SCHEMBL23363752 0.80 TEAD2 (0.34) KDM1ATEAD2PARP1
SCHEMBL23363754 0.80 TEAD2 (0.34) KDM1ATEAD2PARP1
SCHEMBL24750185 0.79 TEAD2 (0.32) TEAD2
SCHEMBL31697652 0.79 TEAD2 (0.32) TEAD2
SCHEMBL24749710 0.74 RXFP1 (0.34) KDM1APARP1
Hydrochloric Acid SCHEMBL31694844 0.73 RXFP1 (0.33) KDM1APARP1
SCHEMBL23363913 0.73 TEAD2 (0.33) TEAD2
SCHEMBL23363909 0.73 TEAD2 (0.33) TEAD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4631573-A2 TEAD INHIBITORS Orion Corporation (FI) 2025-10-15 EP disclosed
EP-4323338-B1 TEAD INHIBITORS ORION CORP (FI) 2025-10-08 EP disclosed
EP-4323338-A1 TEAD INHIBITORS Orion Corporation (FI) 2024-02-21 EP disclosed
CN-117500786-A TEAD inhibitors 奥赖恩公司 2024-02-02 CN disclosed
WO-2022219246-A1 TEAD INHIBITORS ORION CORPORATION (FI) 2022-10-20 WO disclosed