SCHEMBL31697652

SCHEMBL31697652

Nc1cc(/C=C/C2CCC(F)(F)CC2)cc2c1OCO2

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TEAD2 Q15562 1/20 0.32
CYP19A1 P11511 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24750185 1.00 TEAD2 (0.32) TEAD2CYP19A1
SCHEMBL29938019 0.79 KDM1A (0.32) TEAD2
SCHEMBL29149542 0.79 KDM1A (0.32) TEAD2
SCHEMBL24750257 0.79 KDM1A (0.32) TEAD2
SCHEMBL30768248 0.69 P2RX7 (0.35) TEAD2
SCHEMBL29938057 0.69 P2RX7 (0.35) TEAD2
SCHEMBL24750225 0.68 APP (0.51) TEAD2CYP19A1
SCHEMBL23363913 0.64 TEAD2 (0.33) TEAD2
SCHEMBL23363909 0.64 TEAD2 (0.33) TEAD2
SCHEMBL23363752 0.63 TEAD2 (0.34) TEAD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4631573-A2 TEAD INHIBITORS Orion Corporation (FI) 2025-10-15 EP disclosed