Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 1/20 | 0.51 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CFTR | P13569 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ESRRA | P11474 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | RAF1 | P04049 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.44 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24749577 | 1.00 | PTPN7 (0.51) | PTPN7DUSP3MAPTKDM4ECFTR | |
| SCHEMBL24750249 | 0.87 | KDM4E (0.54) | PTPN7DUSP3MAPTKDM4EMAPK1 | |
| SCHEMBL29938669 | 0.87 | KDM4E (0.54) | PTPN7DUSP3MAPTKDM4EMAPK1 | |
| SCHEMBL11212778 | 0.86 | TDP1 (0.57) | MAPTKDM4ECFTRMAPK1LMNA | |
| SCHEMBL4070406 | 0.85 | CFTR (0.62) | MAPTKDM4ECFTRMAPK1ESRRA | |
| SCHEMBL22452952 | 0.83 | MAPT (0.51) | PTPN7DUSP3MAPTKDM4ECFTR | |
| SCHEMBL31042560 | 0.83 | CFTR (0.52) | PTPN7DUSP3CFTRESRRAPPARA | |
| SCHEMBL31042561 | 0.83 | CFTR (0.52) | PTPN7DUSP3CFTRESRRAPPARA | |
| SCHEMBL9503911 | 0.82 | CA12 (0.55) | MAPTKDM4ECFTRMAPK1LMNA | |
| SCHEMBL22453445 | 0.81 | TUBB4A (0.50) | PTPN7DUSP3MAPTKDM4ECFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4323338-A1 | TEAD INHIBITORS | Orion Corporation (FI) | 2024-02-21 | — | — | EP | disclosed |
| WO-2022219246-A1 | TEAD INHIBITORS | ORION CORPORATION (FI) | 2022-10-20 | — | — | WO | disclosed |