Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 15/20 | 0.81 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL557390 | 0.89 | DPP4 (1.00) | DPP4CHRM1CHRM2CHRM3KCNH2 | |
| SCHEMBL637194 | 0.83 | DPP4 (0.73) | DPP4CHRM1CHRM2CHRM3KCNH2 | |
| SCHEMBL27583022 | 0.78 | DPP4 (0.79) | DPP4CHRM1ALDH1A1SMN1; SMN2CHRM2 | |
| SCHEMBL2760536 | 0.78 | DPP4 (0.81) | DPP4CHRM1CHRM2CHRM3KCNH2 | |
| SCHEMBL556234 | 0.78 | DPP4 (0.80) | DPP4CHRM1CHRM2CHRM3KCNH2 | |
| SCHEMBL554889 | 0.78 | DPP4 (1.00) | DPP4CHRM1CHRM2CHRM3KCNH2 | |
| SCHEMBL554890 | 0.78 | DPP4 (1.00) | DPP4CHRM1CHRM2CHRM3KCNH2 | |
| SCHEMBL556080 | 0.78 | DPP4 (1.00) | DPP4CHRM1CHRM2CHRM3KCNH2 | |
| SCHEMBL3038545 | 0.77 | DPP4 (0.63) | DPP4CHRM1KMT2AALDH1A1MEN1 | |
| SCHEMBL3653413 | 0.75 | DPP4 (0.80) | DPP4CHRM1CHRM2CHRM3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100173916-A1 | Xanthine Derivatives, the Preparation Thereof and Their Use as Pharmaceutical Compositions | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100173916-A1 | Xanthine Derivatives, the Preparation Thereof and Their Use as Pharmaceutical Compositions | DPP4, DPP3, DPP7 | DPP4 1/4885CHRM1 334/4885KMT2A 3439/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.