SCHEMBL29938574

SCHEMBL29938574

CC(C)C(=O)COc1c2ccoc2cc2oc(=O)ccc12

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.62
CYP1B1 Q16678 2/20 0.62
LMNA P02545 2/20 0.62
ACHE P22303 1/20 0.62
KDM4E B2RXH2 4/20 0.61
POLB P06746 2/20 0.61
L3MBTL1 Q9Y468 1/20 0.61
CYP1A1 P04798 1/20 0.60
CYP1A2 P05177 1/20 0.60
PGR P06401 1/20 0.60
CYP3A4 P08684 1/20 0.60
ADORA3 P0DMS8 1/20 0.60
CYP2D6 P10635 1/20 0.60
CYP2A6 P11509 1/20 0.60
CYP2C9 P11712 1/20 0.60
KCNA2 P16389 1/20 0.60
TSHR P16473 1/20 0.60
MAOA P21397 1/20 0.60
CYP2C19 P33261 1/20 0.60
HSD17B10 Q99714 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4269808 0.84 ALDH1A1 (0.65) ALDH1A1CYP1B1LMNAACHEKDM4E
SCHEMBL20035921 0.81 KDM4E (0.71) ALDH1A1CYP1B1LMNAACHEKDM4E
SCHEMBL9122678 0.80 ALDH1A1 (0.71) ALDH1A1CYP1B1LMNAACHEKDM4E
SCHEMBL27293969 0.77 KCNA3 (0.65) ALDH1A1CYP1B1LMNAACHEKDM4E
Isoimperatorin SCHEMBL15090959 0.77 ALDH1A1 (1.00) ALDH1A1CYP1B1LMNAACHEKDM4E
Oxypeucedanin Hydrate SCHEMBL15944413 0.76 KDM4E (1.00) ALDH1A1CYP1B1LMNAACHEKDM4E
Oxypeucedanin Hydrate SCHEMBL28952264 0.76 KDM4E (1.00) ALDH1A1CYP1B1LMNAACHEKDM4E
SCHEMBL2799643 0.76 KCNA3 (0.63) ALDH1A1CYP1B1LMNAACHEKDM4E
SCHEMBL30977122 0.76 KDM4E (0.69) ALDH1A1CYP1B1LMNAACHEKDM4E
Oxypeucedanin Hydrate SCHEMBL29425179 0.76 KDM4E (1.00) ALDH1A1CYP1B1LMNAACHEKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113456732-B Composition for removing chloasma and preparation method thereof 河北御芝林生物科技有限公司 2022-09-16 CN disclosed