Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24751507 | 1.00 | LMNA (0.42) | LMNASMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL29938087 | 1.00 | LMNA (0.42) | LMNASMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL29149175 | 0.89 | LMNA (0.42) | LMNASMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL24750263 | 0.89 | LMNA (0.42) | LMNASMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL29149178 | 0.89 | LMNA (0.42) | LMNASMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL24750261 | 0.89 | LMNA (0.42) | LMNASMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL29149332 | 0.89 | LMNA (0.42) | LMNASMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL29149229 | 0.89 | LMNA (0.42) | LMNASMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL29938356 | 0.89 | LMNA (0.42) | LMNASMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL29938386 | 0.89 | LMNA (0.42) | LMNASMN1; SMN2HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4323338-B1 | TEAD INHIBITORS | ORION CORP (FI) | 2025-10-08 | — | — | EP | disclosed |
| EP-4323338-A1 | TEAD INHIBITORS | Orion Corporation (FI) | 2024-02-21 | — | — | EP | disclosed |
| WO-2022219246-A1 | TEAD INHIBITORS | ORION CORPORATION (FI) | 2022-10-20 | — | — | WO | disclosed |