Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 3/20 | 0.50 |
| ▸ | AXL | P30530 | 1/20 | 0.50 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.45 |
| ▸ | IKBKB | O14920 | 3/20 | 0.45 |
| ▸ | CHUK | O15111 | 3/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.45 |
| ▸ | JAK2 | O60674 | 3/20 | 0.45 |
| ▸ | JAK3 | P52333 | 3/20 | 0.45 |
| ▸ | PRKACA | P17612 | 2/20 | 0.45 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.45 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.45 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | PAK4 | O96013 | 1/20 | 0.45 |
| ▸ | CSF1R | P07333 | 1/20 | 0.45 |
| ▸ | RET | P07949 | 1/20 | 0.45 |
| ▸ | IGF1R | P08069 | 1/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.45 |
| ▸ | FLT1 | P17948 | 1/20 | 0.45 |
| ▸ | LTK | P29376 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL179480 | 0.85 | PRKCI (0.53) | PRKCIAXLROCK1IKBKBCHUK | |
| SCHEMBL12915020 | 0.81 | PRKCI (0.49) | PRKCIAXLROCK1IKBKBCHUK | |
| SCHEMBL10298661 | 0.79 | PRKCI (0.47) | PRKCIAXLROCK1IKBKBCHUK | |
| SCHEMBL19286544 | 0.78 | PRKCI (0.46) | PRKCIAXLROCK1IKBKBCHUK | |
| SCHEMBL1823256 | 0.78 | PRKCI (0.53) | PRKCIAXLROCK1IKBKBCHUK | |
| SCHEMBL26953023 | 0.75 | NUDT1 (0.55) | PRKCIAXLROCK1IKBKBCHUK | |
| SCHEMBL26953143 | 0.74 | CIT (0.62) | PRKCIROCK1IKBKBCHUKAURKB | |
| SCHEMBL31735031 | 0.74 | CIT (0.62) | PRKCIROCK1IKBKBCHUKAURKB | |
| SCHEMBL31734974 | 0.73 | IKBKB (0.64) | PRKCIROCK1IKBKBCHUKAURKB | |
| SCHEMBL26953024 | 0.73 | IKBKB (0.64) | PRKCIROCK1IKBKBCHUKAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4326257-A1 | AZETIDINYL-ACETAMIDES AS CXCR7 INHIBITORS | ChemoCentryx, Inc. (US) | 2024-02-28 | — | — | EP | disclosed |
| WO-2022225832-A1 | AZETIDINYL-ACETAMIDES AS CXCR7 INHIBITORS | CHEMOCENTRYX, INC. (US) | 2022-10-27 | — | — | WO | disclosed |