Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.35 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.31 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL736969 | 0.97 | — | — | |
| SCHEMBL22231672 | 0.94 | TP53 (0.42) | TP53SLC7A5GABRR1RNPEPCYP1A2 | |
| SCHEMBL524402 | 0.94 | TP53 (0.42) | TP53SLC7A5GABRR1RNPEPCYP1A2 | |
| SCHEMBL451424 | 0.71 | — | — | |
| SCHEMBL28798975 | 0.69 | TP53 (0.50) | TP53SLC7A5GABRR1RNPEPCYP1A2 | |
| SCHEMBL10012564 | 0.69 | — | — | |
| SCHEMBL15921098 | 0.69 | TP53 (0.42) | TP53SLC7A5GABRR1RNPEPCYP1A2 | |
| SCHEMBL30130066 | 0.68 | — | — | |
| Lactic Acid SCHEMBL8096437 | 0.65 | — | — | |
| Lactic Acid SCHEMBL8096439 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8597959-B2 | Methods of use of solid support material for binding biomolecules | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-12-03 | — | — | US | disclosed |
| US-20100209946-A1 | USES OF WATER-DISPERSIBLE SILICA NANOPARTICLES FOR ATTACHING BIOMOLECULES | 3M INNOVATIVE PROPERTIES COMPANY | 2010-08-19 | — | — | US | disclosed |
| US-20100184103-A1 | METHODS OF USE OF SOLID SUPPORT MATERIAL FOR BINDING BIOMOLECULES | 3M INNOVATIVE PROPERTIES COMPANY | 2010-07-22 | — | — | US | disclosed |
| EP-2140264-A1 | METHODS OF USE OF SOLID SUPPORT MATERIAL FOR BINDING BIOMOLECULES | 3M Innovative Properties Company (US) | 2010-01-06 | — | — | EP | disclosed |
| EP-2137533-A2 | USES OF WATER-DISPERSIBLE SILICA NANOPARTICLES FOR ATTACHING BIOMOLECULES | 3M Innovative Properties Company (US) | 2009-12-30 | — | — | EP | disclosed |
| WO-2009009188-A2 | USES OF WATER-DISPERSIBLE SILICA NANOPARTICLES FOR ATTACHING BIOMOLECULES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2009-01-15 | — | — | WO | disclosed |
| WO-2008131063-A1 | METHODS OF USE OF SOLID SUPPORT MATERIAL FOR BINDING BIOMOLECULES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2008-10-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100209946-A1 | USES OF WATER-DISPERSIBLE SILICA NANOPARTICLES FOR ATTACHING BIOMOLECULES | CD44, SELP, EPCAM | TP53 318/4885SLC7A5 1539/4885GABRR1 2678/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.