SCHEMBL2993952

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2995571	0.85	KDM4E (0.42)	KDRCDK2CCNA2PLK1CCNA1
	SCHEMBL5231212	0.82	HTR2A (0.39)	KDRCDK2CCNA2PLK1CCNA1
	SCHEMBL2995670	0.81	HTR2A (0.42)	KDRCDK2CCNA2PLK1CCNA1
	SCHEMBL2995376	0.80	HTR2A (0.43)	KDRCDK2CCNA2PLK1CCNA1
	SCHEMBL2993953	0.76	KDM4E (0.49)	CDK2PLK4DAPK3CHEK2CDK1
	SCHEMBL1173816	0.74	PARP1 (0.52)	HTR2AKCNH2HTR2CDRD2
	SCHEMBL2987900	0.72	HTR2A (0.39)	KDRCDK2CCNA2PLK1CCNA1
	SCHEMBL13211532	0.71	PTGS1 (0.46)	MAPK9HTR2AKCNH2HTR2CDRD2
	SCHEMBL2997440	0.71	GCGR (0.40)	PRKAA1HTR2AKCNH2
	SCHEMBL13211500	0.71	PLK4 (0.39)	KDRCDK2PLK1PLK4DAPK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.