SCHEMBL29939666

SCHEMBL29939666

CC(C)C[C@H](NC(=O)[C@H](CO)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](CS)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ACE P12821 1/20 0.50
MME P08473 7/20 0.47
KDM4E B2RXH2 1/20 0.42
MAPT P10636 1/20 0.42
THRB P10828 1/20 0.42
ALOX15 P16050 1/20 0.42
NFKB1 P19838 1/20 0.42
PTGS2 P35354 1/20 0.42
THPO P40225 1/20 0.42
RECQL P46063 1/20 0.42
BLM P54132 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
ALDH1A1 P00352 2/20 0.41
LAP3 P28838 3/20 0.40
MEN1 O00255 1/20 0.40
LMNA P02545 1/20 0.40
KMT2A Q03164 1/20 0.40
SLC7A5 Q01650 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30717674 0.94 MME (0.47) ACEMMEMAPTALDH1A1LAP3
SCHEMBL30204291 0.93 ACE (0.49) ACEMMEKDM4EMAPTTHRB
SCHEMBL30123555 0.92 ACE (0.53) ACEMMEKDM4EMAPTTHRB
SCHEMBL29449455 0.90 MME (0.56) MMEMAPTALDH1A1LAP3MEN1
SCHEMBL30288027 0.90 ACE (0.51) ACEMMEKDM4EMAPTTHRB
SCHEMBL29564354 0.90 ACE (0.51) ACEMMEKDM4EMAPTTHRB
SCHEMBL30288039 0.90 ACE (0.51) ACEMMEKDM4EMAPTTHRB
SCHEMBL30924740 0.90 PDCD1LG2 (0.48) ACEMMEKDM4EMAPTTHRB
SCHEMBL30311049 0.88 ACE (0.56) ACEMMEKDM4EMAPTTHRB
SCHEMBL30010902 0.88 ACE (0.56) ACEMMEKDM4EMAPTTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230103704-A1 HUMAN ANTI-INFLAMMATORY PEPTIDES FOR THE INHALATORY TREATMENT OF INFLAMMATORY PULMONARY ISSUES ADVITA LIFESCIENCE GMBH (DE) 2023-04-06 US disclosed
CN-115066254-A Human anti-inflammatory peptides for inhalation treatment of inflammatory lung diseases 阿德维塔生命科学有限责任公司 2022-09-16 CN disclosed