Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.48 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 6/20 | 0.43 |
| ▸ | ECE1 | P42892 | 2/20 | 0.42 |
| ▸ | BACE1 | P56817 | 3/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945568 | 0.91 | PDCD1LG2 (0.53) | PDCD1LG2CD274MMEECE1BACE1 | |
| SCHEMBL30288007 | 0.91 | PDCD1LG2 (0.49) | PDCD1LG2CD274ACEMMEECE1 | |
| SCHEMBL30390466 | 0.90 | ACE (0.50) | ACEMMEECE1BACE1CTSD | |
| SCHEMBL29939666 | 0.90 | ACE (0.50) | ACEMMEKDM4EMAPTTHRB | |
| SCHEMBL30287994 | 0.88 | PDCD1LG2 (0.47) | PDCD1LG2CD274ACEMMEECE1 | |
| SCHEMBL14571185 | 0.87 | BACE1 (0.45) | ACEMMEECE1BACE1CTSD | |
| SCHEMBL30571137 | 0.86 | PDCD1LG2 (0.47) | PDCD1LG2CD274MMEECE1BACE1 | |
| SCHEMBL29695578 | 0.86 | PDCD1LG2 (0.46) | PDCD1LG2CD274MMEECE1BACE1 | |
| SCHEMBL30749754 | 0.85 | PDCD1LG2 (0.46) | PDCD1LG2CD274ACEMMEECE1 | |
| SCHEMBL30060708 | 0.85 | ECE1 (0.45) | MMEECE1BACE1CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240190917-A1 | PEPTIDES AND METHODS FOR REDUCING SKIN PIGMENTATION | GLO PHARMA, INC. | 2024-06-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240190917-A1 | PEPTIDES AND METHODS FOR REDUCING SKIN PIGMENTATION | MC1R, TYR, MC5R | PDCD1LG2 624/4885CD274 742/4885ACE 4029/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.