⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31485673 | 0.84 | — | — | |
| SCHEMBL427006 | 0.78 | — | — | |
| SCHEMBL19658194 | 0.78 | CYP2C19 (0.32) | — | |
| SCHEMBL32691219 | 0.76 | — | — | |
| SCHEMBL17599051 | 0.73 | — | — | |
| SCHEMBL17048944 | 0.73 | — | — | |
| SCHEMBL31380559 | 0.71 | — | — | |
| SCHEMBL16412698 | 0.70 | ADH1B (0.42) | — | |
| SCHEMBL24214199 | 0.69 | — | — | |
| SCHEMBL18658615 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4308562-A1 | PYRAZOLOPYRIDINE DERIVATIVES AND USES THEREOF | Novartis AG (CH) | 2024-01-24 | — | — | EP | disclosed |
| WO-2022195454-A1 | PYRAZOLOPYRIDINE DERIVATIVES AND USES THEREOF | NOVARTIS AG (CH) | 2022-09-22 | — | — | WO | disclosed |