Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 2/20 | 0.53 |
| ▸ | DRD1 | P21728 | 8/20 | 0.53 |
| ▸ | DRD5 | P21918 | 8/20 | 0.53 |
| ▸ | DRD2 | P14416 | 8/20 | 0.53 |
| ▸ | DRD3 | P35462 | 8/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.52 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | DRD4 | P21917 | 5/20 | 0.49 |
| ▸ | BCL2 | P10415 | 1/20 | 0.49 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL43307 | 1.00 | METAP1 (0.53) | METAP1DRD1DRD5DRD2DRD3 | |
| SCHEMBL227363 | 0.93 | CYP1A2 (0.60) | METAP1DRD1DRD5DRD2DRD3 | |
| Sulfurous Acid SCHEMBL6400949 | 0.92 | CYP1A2 (0.47) | METAP1DRD1DRD5DRD2DRD3 | |
| SCHEMBL3813236 | 0.89 | DRD1 (0.52) | METAP1DRD1DRD5DRD2DRD3 | |
| SCHEMBL2062199 | 0.89 | DRD1 (0.54) | METAP1DRD1DRD5DRD2DRD3 | |
| SCHEMBL4041676 | 0.86 | METAP1 (0.58) | METAP1DRD1DRD5DRD2DRD3 | |
| SCHEMBL27844091 | 0.84 | CYP1A2 (0.49) | METAP1DRD1DRD5DRD2DRD3 | |
| SCHEMBL27843792 | 0.84 | CYP1A2 (0.49) | METAP1DRD1DRD5DRD2DRD3 | |
| SCHEMBL228868 | 0.82 | DRD1 (0.56) | METAP1DRD1DRD5DRD2DRD3 | |
| SCHEMBL14172824 | 0.82 | DRD1 (0.56) | METAP1DRD1DRD5DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122036628-A | Iron death inhibitor, preparation method and application thereof | 福建医科大学 | 2026-05-15 | — | — | CN | disclosed |
| CN-115594669-B | Parallel ring derivative and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2024-11-05 | — | — | CN | disclosed |
| CN-117466773-A | Preparation method of eletinib intermediate | 上海药坦药物研究开发有限公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-115340523-B | Compound with ALK inhibitory activity and preparation method and application thereof | 盛世泰科生物医药技术(苏州)股份有限公司 | 2023-12-15 | — | — | CN | disclosed |
| CN-117024410-A | Airotinib intermediate and preparation method thereof | 上海药坦药物研究开发有限公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-115594669-A | Fused ring derivative and preparation method and medical application thereof | 深圳信立泰药业股份有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |
| CN-115340523-A | Compound with ALK inhibitory activity and preparation method and application thereof | 盛世泰科生物医药技术(苏州)有限公司 | 2022-11-15 | — | — | CN | disclosed |