Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 2/20 | 0.53 |
| ▸ | DRD1 | P21728 | 8/20 | 0.53 |
| ▸ | DRD5 | P21918 | 8/20 | 0.53 |
| ▸ | DRD2 | P14416 | 8/20 | 0.53 |
| ▸ | DRD3 | P35462 | 8/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.52 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | DRD4 | P21917 | 5/20 | 0.49 |
| ▸ | BCL2 | P10415 | 1/20 | 0.49 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29940518 | 1.00 | METAP1 (0.53) | METAP1DRD1DRD5DRD2DRD3 | |
| SCHEMBL227363 | 0.93 | CYP1A2 (0.60) | METAP1DRD1DRD5DRD2DRD3 | |
| Sulfurous Acid SCHEMBL6400949 | 0.92 | CYP1A2 (0.47) | METAP1DRD1DRD5DRD2DRD3 | |
| SCHEMBL3813236 | 0.89 | DRD1 (0.52) | METAP1DRD1DRD5DRD2DRD3 | |
| SCHEMBL2062199 | 0.89 | DRD1 (0.54) | METAP1DRD1DRD5DRD2DRD3 | |
| SCHEMBL4041676 | 0.86 | METAP1 (0.58) | METAP1DRD1DRD5DRD2DRD3 | |
| SCHEMBL27844091 | 0.84 | CYP1A2 (0.49) | METAP1DRD1DRD5DRD2DRD3 | |
| SCHEMBL27843792 | 0.84 | CYP1A2 (0.49) | METAP1DRD1DRD5DRD2DRD3 | |
| SCHEMBL228868 | 0.82 | DRD1 (0.56) | METAP1DRD1DRD5DRD2DRD3 | |
| SCHEMBL14172824 | 0.82 | DRD1 (0.56) | METAP1DRD1DRD5DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 642 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109678788-B | 1, 2-diaryl indole, derivative and synthetic method thereof | 湘潭大学 | 2021-05-04 | — | — | CN | claimed |
| CN-107722146-B | Method for producing solid polyaluminoxane composition | 三井化学株式会社 | 2021-02-26 | — | — | CN | claimed |
| CN-107619386-B | Aromatic ring [ c ] carbazole derivative and synthesis method thereof | 湘潭大学 | 2020-10-13 | — | — | CN | claimed |
| CN-107619386-A | A kind of aromatic ring simultaneously [c] carbazole analog derivative and its synthetic method | 湘潭大学 | 2018-01-23 | — | — | CN | claimed |
| CN-104910002-B | A kind of preparation method of dezocine key intermediate | 温州医科大学 | 2017-11-03 | — | — | CN | claimed |
| EP-2623593-B1 | NOVEL AMINOTRANSFERASE AND GENE ENCODING SAME, AND USE OF THE AMINOTRANSFERASE AND THE GENE | KANEKA CORP (JP) | 2017-07-12 | — | — | EP | claimed |
| EP-2684953-B1 | MODIFIED AMINOTRANSFERASE, GENE THEREOF, AND METHOD FOR PRODUCING OPTICALLY ACTIVE AMINO COMPOUND USING SAME | KANEKA CORP (JP) | 2017-06-28 | — | — | EP | claimed |
| EP-2623595-B1 | NOVEL TRANSAMINASE SHOWING HIGH ACTIVITY FOR GLUTAMIC ACID, GENE ENCODING SAME, AND METHOD FOR UTILIZATION THEREOF | KANEKA CORP (JP) | 2016-11-02 | — | — | EP | claimed |
| US-9481870-B2 | Nucleic acid encoding a polypeptide having aminotransferase activity, vectors and host cells comprising the nucleic acid | KANEKA CORPORATION (JP) | 2016-11-01 | — | — | US | claimed |
| CN-103534353-B | Modification type aminopherase, its gene and utilize their manufacture method of optical activity amino-compound | 株式会社钟化 | 2016-08-17 | — | — | CN | claimed |
| EP-1553170-B1 | NOVEL CARBONYL REDUCTASE, GENE THEREOF AND METHOD OF USING THE SAME | KANEKA CORP (JP) | 2012-06-27 | — | — | EP | claimed |
| US-7531329-B2 | Carbonyl reductase, gene thereof and method of using the same | KANEKA CORPORATION (JP) | 2009-05-12 | — | — | US | claimed |
| EP-1889907-A1 | NOVEL AMINO GROUP TRANSFERASE, GENE ENCODING THE SAME AND METHOD OF USING THE SAME | Kaneka Corporation (JP) | 2008-02-20 | — | — | EP | claimed |
| US-20070178565-A1 | Novel carbonyl reductase, gene thereof and method of using the same | KANEKA CORPORATION | 2007-08-02 | — | — | US | claimed |
| US-7074770-B1 | Method of DNA vaccination | SMITHKLINE BEECHAM CORPORATION (US) | 2006-07-11 | — | — | US | claimed |
| US-20060035357-A1 | Novel carbonyl reductase, gene thereof and method of using the same | KANEKA CORPORATION (JP) | 2006-02-16 | — | — | US | claimed |
| EP-1553170-A1 | NOVEL CARBONYL REDUCTASE, GENE THEREOF AND METHOD OF USING THE SAME | KANEKA CORPORATION (JP) | 2005-07-13 | — | — | EP | claimed |
| EP-1107785-A1 | METHOD OF DNA VACCINATION | GLAXO GROUP LIMITED (GB) | 2001-06-20 | — | — | EP | claimed |
| WO-2000012121-A1 | METHOD OF DNA VACCINATION | GLAXO GROUP LIMITED (GB) | 2000-03-09 | — | — | WO | claimed |
| EP-0286516-B1 | Amino-5,6,7,8-tetrahydro-naphtho[2,3b]furan derivatives, processes for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-03-18 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070178565-A1 | Novel carbonyl reductase, gene thereof and method of using the same | PYCR1, CBR3, CBR1 | METAP1 1034/4885DRD1 2439/4885DRD5 2043/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.