Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MT-CO2 | P00403 | 15/20 | 1.00 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.69 |
| ▸ | TOP1 | P11387 | 4/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | TTR | P02766 | 1/20 | 0.56 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | PGR | P06401 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
| ▸ | AR | P10275 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28905882 | 1.00 | MT-CO2 (1.00) | MT-CO2PTGS2TOP1MEN1USP2 | |
| SCHEMBL28687925 | 0.84 | MT-CO2 (0.76) | MT-CO2PTGS2TOP1MEN1USP2 | |
| SCHEMBL29940782 | 0.84 | MT-CO2 (0.74) | MT-CO2PTGS2TOP1MEN1USP2 | |
| SCHEMBL28905877 | 0.84 | MT-CO2 (0.74) | MT-CO2PTGS2TOP1MEN1USP2 | |
| SCHEMBL28661454 | 0.81 | MT-CO2 (1.00) | MT-CO2PTGS2TOP1MEN1USP2 | |
| SCHEMBL28905922 | 0.81 | MT-CO2 (0.72) | MT-CO2PTGS2TOP1MEN1USP2 | |
| SCHEMBL28905892 | 0.81 | MT-CO2 (0.71) | MT-CO2PTGS2TOP1MEN1USP2 | |
| SCHEMBL28679799 | 0.81 | MT-CO2 (0.71) | MT-CO2PTGS2TOP1MEN1USP2 | |
| SCHEMBL28905901 | 0.81 | MT-CO2 (0.71) | MT-CO2PTGS2TOP1MEN1USP2 | |
| SCHEMBL29940581 | 0.81 | MT-CO2 (0.71) | MT-CO2PTGS2TOP1MEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115108931-A | Tofenamic acid derivative and preparation and application thereof | 南华大学附属第一医院 | 2022-09-27 | — | — | CN | disclosed |