Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 15/20 | 0.49 |
| ▸ | HTR6 | P50406 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | HTR1B | P28222 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28796216 | 1.00 | SLC6A4 (0.49) | SLC6A4HTR6SLC6A2SLC6A3HTR1A | |
| SCHEMBL29940850 | 0.84 | KMT2A (0.38) | SLC6A4HTR6SLC6A2SLC6A3HTR1A | |
| SCHEMBL31490967 | 0.83 | SLC6A4 (0.49) | SLC6A4HTR6SLC6A2SLC6A3HTR1A | |
| SCHEMBL20846187 | 0.81 | HTR6 (0.48) | SLC6A4HTR6SLC6A2SLC6A3 | |
| SCHEMBL28099154 | 0.80 | SLC6A4 (0.46) | SLC6A4HTR6SLC6A2SLC6A3HTR1A | |
| SCHEMBL29994158 | 0.77 | SLC6A4 (0.52) | SLC6A4HTR6SLC6A2SLC6A3HTR1A | |
| SCHEMBL733659 | 0.77 | SLC6A4 (0.52) | SLC6A4HTR6SLC6A2SLC6A3HTR1A | |
| SCHEMBL13323651 | 0.77 | HTR6 (0.63) | SLC6A4HTR6SLC6A2SLC6A3HTR1A | |
| SCHEMBL28521686 | 0.76 | IDO1 (0.67) | IDO1 | |
| SCHEMBL31397678 | 0.76 | IDO1 (0.67) | IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109942478-B | Synthetic method of 3-methylthio indole derivative | 南京理工大学 | 2022-07-22 | — | — | CN | disclosed |