Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.34 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | GAA | P10253 | 5/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29940336 | 1.00 | MAPT (0.34) | MAPTKMT2AMEN1POLBRAB9A | |
| SCHEMBL20569821 | 1.00 | MAPT (0.34) | MAPTKMT2AMEN1POLBRAB9A | |
| SCHEMBL20943869 | 0.77 | FGFR1 (0.46) | — | |
| SCHEMBL18708653 | 0.77 | FGFR1 (0.46) | — | |
| SCHEMBL4403044 | 0.68 | KDM4E (0.37) | KDM4EHTTALDH1A1MAPK1 | |
| SCHEMBL4403038 | 0.68 | KDM4E (0.37) | KDM4EHTTALDH1A1MAPK1 | |
| SCHEMBL29940550 | 0.68 | PDE5A (0.36) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL16176863 | 0.68 | PDE5A (0.36) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL20073537 | 0.67 | HPGD (0.38) | MAPTKMT2AMEN1POLBRAB9A | |
| SCHEMBL20225783 | 0.67 | NPC1 (0.43) | MAPTKMT2AMEN1POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115785090-A | Crystalline forms of FGFR inhibitors and methods of making the same | 因赛特公司 | 2023-03-14 | — | — | CN | disclosed |
| CN-111148745-B | Crystalline forms of FGFR inhibitors and methods of making the same | 因赛特公司 | 2022-11-11 | — | — | CN | disclosed |