Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 20/20 | 0.60 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | EML4 | Q9HC35 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28913346 | 1.00 | ALK (0.60) | ALKKDREML4 | |
| SCHEMBL30760744 | 0.89 | ALK (0.54) | ALKKDREML4 | |
| SCHEMBL27087601 | 0.87 | ALK (0.59) | ALKKDREML4 | |
| SCHEMBL29940520 | 0.87 | ALK (0.59) | ALKKDREML4 | |
| SCHEMBL28913313 | 0.85 | ALK (0.56) | ALKKDREML4 | |
| SCHEMBL29940669 | 0.85 | ALK (0.48) | ALK | |
| SCHEMBL27087527 | 0.85 | ALK (0.48) | ALK | |
| SCHEMBL27087536 | 0.84 | ALK (0.58) | ALKKDREML4 | |
| SCHEMBL898251 | 0.82 | ALK (0.79) | ALK | |
| SCHEMBL27087607 | 0.82 | ALK (0.52) | ALKKDREML4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115340523-B | Compound with ALK inhibitory activity and preparation method and application thereof | 盛世泰科生物医药技术(苏州)股份有限公司 | 2023-12-15 | — | — | CN | disclosed |
| WO-2022237813-A1 | COMPOUND HAVING ALK INHIBITORY ACTIVITY, PREPARATION METHOD THEREFOR AND USE THEREOF | 盛世泰科生物医药技术(苏州)有限公司 | 2022-11-17 | — | — | WO | disclosed |
| CN-115340523-A | Compound with ALK inhibitory activity and preparation method and application thereof | 盛世泰科生物医药技术(苏州)有限公司 | 2022-11-15 | — | — | CN | disclosed |