Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 6/20 | 0.48 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | NOTCH1 | P46531 | 4/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | FPR2 | P25090 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27087527 | 1.00 | ALK (0.48) | ALKDPP4BRD3KDM4EMAPT | |
| SCHEMBL30009833 | 0.89 | ALK (0.40) | ALK | |
| SCHEMBL30009789 | 0.86 | ALK (0.40) | ALK | |
| SCHEMBL29940758 | 0.85 | ALK (0.60) | ALK | |
| SCHEMBL28913346 | 0.85 | ALK (0.60) | ALK | |
| SCHEMBL27087525 | 0.83 | ALK (0.41) | ALKPDE4A | |
| SCHEMBL27087547 | 0.81 | ALK (0.36) | ALK | |
| SCHEMBL23291507 | 0.75 | MAPT (0.49) | DPP4KDM4EMAPTTHRBFPR2 | |
| SCHEMBL31222846 | 0.75 | MAPT (0.49) | DPP4KDM4EMAPTTHRBFPR2 | |
| SCHEMBL31738645 | 0.74 | KDM4E (0.45) | DPP4KDM4EMAPTTHRBSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115340523-B | Compound with ALK inhibitory activity and preparation method and application thereof | 盛世泰科生物医药技术(苏州)股份有限公司 | 2023-12-15 | — | — | CN | disclosed |
| CN-115340523-A | Compound with ALK inhibitory activity and preparation method and application thereof | 盛世泰科生物医药技术(苏州)有限公司 | 2022-11-15 | — | — | CN | disclosed |