Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MT-CO2 | P00403 | 10/20 | 1.00 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.60 |
| ▸ | TOP1 | P11387 | 3/20 | 0.60 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.57 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.57 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28905878 | 1.00 | MT-CO2 (1.00) | MT-CO2PTGS2TOP1CHRM5CHRM1 | |
| SCHEMBL29940382 | 0.92 | MT-CO2 (1.00) | MT-CO2PTGS2TOP1LMNARAB9A | |
| SCHEMBL28905895 | 0.92 | MT-CO2 (1.00) | MT-CO2PTGS2TOP1LMNARAB9A | |
| SCHEMBL29941121 | 0.91 | MT-CO2 (0.88) | MT-CO2PTGS2TOP1LMNARAB9A | |
| SCHEMBL28905909 | 0.91 | MT-CO2 (0.88) | MT-CO2PTGS2TOP1LMNARAB9A | |
| SCHEMBL29940792 | 0.91 | MT-CO2 (1.00) | MT-CO2PTGS2TOP1LMNARAB9A | |
| SCHEMBL28905899 | 0.91 | MT-CO2 (1.00) | MT-CO2PTGS2TOP1LMNARAB9A | |
| SCHEMBL28905881 | 0.89 | MT-CO2 (1.00) | MT-CO2PTGS2TOP1LMNARAB9A | |
| SCHEMBL29940745 | 0.89 | MT-CO2 (1.00) | MT-CO2PTGS2TOP1LMNARAB9A | |
| SCHEMBL28905908 | 0.87 | MT-CO2 (1.00) | MT-CO2PTGS2TOP1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115108931-A | Tofenamic acid derivative and preparation and application thereof | 南华大学附属第一医院 | 2022-09-27 | — | — | CN | disclosed |