Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | ACP1 | P24666 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.43 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.43 |
| ▸ | PNPO | Q9NVS9 | 1/20 | 0.42 |
| ▸ | INPPL1 | O15357 | 11/20 | 0.42 |
| ▸ | INPP5A | Q14642 | 6/20 | 0.42 |
| ▸ | INPP5B | P32019 | 2/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12677154 | 0.75 | CYP3A4 (0.40) | P2RX2KDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL30413789 | 0.71 | ESR1 (0.69) | ESR1PTGS1ACP1PDE4AP2RX1 | |
| SCHEMBL12727925 | 0.71 | ESR1 (0.69) | ESR1PTGS1ACP1PDE4AP2RX1 | |
| SCHEMBL28122353 | 0.70 | INPPL1 (0.50) | INPPL1INPP5AINPP5BAKT1KDM4E | |
| Water SCHEMBL29016468 | 0.68 | P2RX2 (0.53) | ESR1PTGS1ACP1PDE4AP2RX1 | |
| SCHEMBL4577077 | 0.68 | KDM4E (0.49) | ESR1PTGS1ACP1PDE4AP2RX1 | |
| SCHEMBL5667259 | 0.68 | PNPO (0.39) | ESR1PTGS1ACP1PDE4AP2RX1 | |
| SCHEMBL28726252 | 0.67 | ESR1 (0.52) | ESR1PTGS1ACP1PDE4AP2RX1 | |
| SCHEMBL29711865 | 0.67 | ESR1 (0.52) | ESR1PTGS1ACP1PDE4AP2RX1 | |
| SCHEMBL4576389 | 0.67 | KDM4E (0.47) | ESR1PTGS1ACP1PDE4AP2RX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11446398-B2 | Regulated biocircuit systems | OBSIDIAN THERAPEUTICS, INC. (US) | 2022-09-20 | — | — | US | disclosed |