Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 18/20 | 0.52 |
| ▸ | MAP2K2 | P36507 | 3/20 | 0.51 |
| ▸ | CES2 | O00748 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | CES1 | P23141 | 1/20 | 0.49 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6295923 | 0.91 | MAP2K1 (0.55) | MAP2K1MAP2K2CES2BCHECES1 | |
| SCHEMBL6295965 | 0.86 | CES2 (0.47) | MAP2K1MAP2K2CES2BCHECES1 | |
| SCHEMBL6295843 | 0.82 | CES2 (0.44) | MAP2K1MAP2K2CES2BCHECES1 | |
| SCHEMBL6291260 | 0.81 | KAT6A (0.45) | MAP2K1CES2BCHECES1KAT6A | |
| SCHEMBL9703918 | 0.81 | HDAC3 (0.47) | MAP2K1MAP2K2 | |
| SCHEMBL2646708 | 0.78 | CES2 (0.61) | CES2BCHECES1KAT6A | |
| SCHEMBL4862965 | 0.78 | CES2 (0.45) | MAP2K1CES2BCHECES1KAT6A | |
| SCHEMBL6291256 | 0.78 | CES2 (0.45) | MAP2K1MAP2K2CES2BCHECES1 | |
| SCHEMBL4861283 | 0.77 | MAPK1 (0.47) | MAP2K1MAP2K2CES2BCHECES1 | |
| SCHEMBL4861405 | 0.77 | CES2 (0.41) | MAP2K1MAP2K2CES2BCHECES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11446398-B2 | Regulated biocircuit systems | OBSIDIAN THERAPEUTICS, INC. (US) | 2022-09-20 | — | — | US | disclosed |