Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 1/20 | 0.63 |
| ▸ | PLAU | P00749 | 1/20 | 0.63 |
| ▸ | PLAT | P00750 | 1/20 | 0.63 |
| ▸ | KLK1 | P06870 | 1/20 | 0.63 |
| ▸ | HTR2C | P28335 | 2/20 | 0.56 |
| ▸ | HTR2B | P41595 | 1/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | MAOB | P27338 | 5/20 | 0.47 |
| ▸ | KDM1A | O60341 | 4/20 | 0.47 |
| ▸ | MAOA | P21397 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.45 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21067278 | 1.00 | PLG (0.63) | PLGPLAUPLATKLK1HTR2C | |
| SCHEMBL31596842 | 0.88 | HTR2C (0.51) | PLGPLAUPLATKLK1HTR2C | |
| SCHEMBL28829976 | 0.83 | CYP1A2 (0.55) | PLGPLAUPLATKLK1HTR2C | |
| SCHEMBL3612181 | 0.81 | PLG (0.52) | PLGPLAUPLATKLK1HTR2C | |
| SCHEMBL20656974 | 0.79 | HTR2C (0.61) | HTR2CHTR2BSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL12972028 | 0.79 | HTR2C (0.61) | HTR2CHTR2BSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL8845464 | 0.79 | MAOB (0.65) | HTR2CHTR2BSLC6A2SLC6A3CYP2D6 | |
| SCHEMBL10540521 | 0.79 | MAOB (0.65) | HTR2CHTR2BSLC6A2SLC6A3CYP2D6 | |
| SCHEMBL2261976 | 0.79 | MAOB (0.65) | HTR2CHTR2BSLC6A2SLC6A3CYP2D6 | |
| SCHEMBL4312320 | 0.78 | PLAU (1.00) | PLGPLAUPLATKLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11446398-B2 | Regulated biocircuit systems | OBSIDIAN THERAPEUTICS, INC. (US) | 2022-09-20 | — | — | US | disclosed |