Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 3/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23389212 | 1.00 | KMT2A (0.47) | KMT2AMEN1HRH3MAPTAKR1C3 | |
| SCHEMBL23389209 | 1.00 | KMT2A (0.47) | KMT2AMEN1HRH3MAPTAKR1C3 | |
| SCHEMBL23419132 | 0.86 | FPR2 (0.42) | KMT2AMEN1HRH3AKR1C3FPR2 | |
| SCHEMBL29943939 | 0.86 | FPR2 (0.42) | KMT2AMEN1HRH3AKR1C3FPR2 | |
| SCHEMBL23389122 | 0.86 | FPR2 (0.42) | KMT2AMEN1HRH3AKR1C3FPR2 | |
| SCHEMBL25991354 | 0.85 | HRH4 (0.51) | KMT2AMEN1HRH3AKR1C3DRD3 | |
| SCHEMBL23419189 | 0.83 | FPR2 (0.55) | KMT2AMEN1HRH3MAPTAKR1C3 | |
| SCHEMBL23389233 | 0.81 | KMT2A (0.46) | KMT2AMEN1HRH3MAPTHRH4 | |
| SCHEMBL23389232 | 0.81 | KMT2A (0.46) | KMT2AMEN1HRH3MAPTHRH4 | |
| SCHEMBL23389182 | 0.80 | KMT2A (0.44) | KMT2AMEN1HRH3MAPTAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115335039-A | Caspase 6 inhibitors and uses thereof | 加利福尼亚大学董事会 | 2022-11-11 | — | — | CN | disclosed |
| EP-4061341-A1 | CASPASE 6 INHIBITORS AND USES THEREOF | The Regents of the University of California (US) | 2022-09-28 | — | — | EP | disclosed |