Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 5/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.30 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.30 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.30 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16738832 | 1.00 | S1PR1 (0.33) | S1PR1S1PR2S1PR4S1PR3S1PR5 | |
| SCHEMBL25990935 | 1.00 | S1PR1 (0.33) | S1PR1S1PR2S1PR4S1PR3S1PR5 | |
| SCHEMBL9280511 | 0.84 | DRD2 (0.37) | S1PR1S1PR2S1PR4S1PR3S1PR5 | |
| SCHEMBL20269787 | 0.82 | — | — | |
| SCHEMBL20269785 | 0.82 | — | — | |
| SCHEMBL29944717 | 0.82 | — | — | |
| SCHEMBL20269395 | 0.81 | CYP19A1 (0.33) | — | |
| SCHEMBL29944706 | 0.81 | CYP19A1 (0.33) | — | |
| SCHEMBL20269397 | 0.81 | CYP19A1 (0.33) | — | |
| SCHEMBL15286851 | 0.80 | CYP11B1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3555076-B1 | NOVEL PHENYL PROPIONIC ACID DERIVATIVES AND USES THEREOF | IL DONG PHARMA (KR) | 2023-04-05 | — | — | EP | disclosed |
| CN-110049984-B | Phenylpropionic acid derivatives and use thereof | 日东制药株式会社 | 2022-11-15 | — | — | CN | disclosed |