Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 6/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11127572 | 1.00 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL2740452 | 1.00 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL13105980 | 1.00 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL12200484 | 1.00 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL13555731 | 0.94 | THRB (0.61) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL31250026 | 0.94 | THRB (0.61) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL27688824 | 0.93 | TSHR (0.62) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL5909577 | 0.92 | TSHR (0.61) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL6115523 | 0.92 | TSHR (0.61) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL4933888 | 0.92 | TSHR (0.61) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2516493-B2 | USE OF NETWORK COMPOSITIONS IN COSMETICS OR PERSONAL CARE PRODUCTS | MOMENTIVE PERFORMANCE MAT INC (US) | 2022-11-16 | — | — | EP | claimed |