Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.80 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.52 |
| ▸ | MAT2A | P31153 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | EED | O75530 | 1/20 | 0.47 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.47 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.47 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.47 |
| ▸ | RBBP7 | Q16576 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26695307 | 1.00 | KDM4E (0.80) | KDM4EKMT2AL3MBTL1PSMD14OPRM1 | |
| SCHEMBL309746 | 0.89 | KDM4E (1.00) | KDM4EKMT2AL3MBTL1PSMD14OPRM1 | |
| SCHEMBL29944921 | 0.89 | KDM4E (1.00) | KDM4EKMT2AL3MBTL1PSMD14OPRM1 | |
| SCHEMBL26695338 | 0.85 | KDM4E (0.78) | KDM4EKMT2AL3MBTL1PSMD14OPRM1 | |
| SCHEMBL29944919 | 0.81 | L3MBTL1 (0.57) | KDM4EKMT2AL3MBTL1PSMD14OPRM1 | |
| SCHEMBL26695380 | 0.81 | L3MBTL1 (0.57) | KDM4EKMT2AL3MBTL1PSMD14OPRM1 | |
| SCHEMBL23579791 | 0.80 | KDM4E (0.70) | KDM4EKMT2AL3MBTL1PSMD14OPRM1 | |
| SCHEMBL30033251 | 0.80 | KDM4E (0.70) | KDM4EKMT2AL3MBTL1PSMD14OPRM1 | |
| SCHEMBL1695004 | 0.79 | KDM4E (0.69) | KDM4EKMT2AL3MBTL1PSMD14MAT2A | |
| SCHEMBL1695347 | 0.78 | PPARA (0.54) | KDM4EKMT2AL3MBTL1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220306627-A1 | COMPOSITIONS AND METHODS FOR INHIBITING VIRUS PROTEIN 2C ACTIVITY AND FOR PREVENTING AND TREATING NON-POLIO ENTEROVIRUS INFECTION | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA | 2022-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220306627-A1 | COMPOSITIONS AND METHODS FOR INHIBITING VIRUS PROTEIN 2C ACTIVITY AND FOR PREVENTING AND TREATING NON-POLIO ENTEROVIRUS INFECTION | GTF3C3, VDAC3, GTF3C5 | KDM4E 3370/4885KMT2A 3570/4885L3MBTL1 3422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.