Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
| ▸ | TYMS | P04818 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24705193 | 0.75 | ADORA2A (0.41) | MAPTGAAKDM4EALDH1A1CYP1A2 | |
| SCHEMBL29727969 | 0.75 | ADORA2A (0.41) | MAPTGAAKDM4EALDH1A1CYP1A2 | |
| SCHEMBL25419299 | 0.75 | PARP1 (0.37) | PARP1TYMSTYMPDAODDO | |
| SCHEMBL28846841 | 0.74 | PDE3B (0.45) | MAPTGAAKDM4EALDH1A1CYP1A2 | |
| SCHEMBL824381 | 0.71 | PIK3CG (0.56) | MAPTGAAKDM4EALDH1A1CYP1A2 | |
| SCHEMBL30065138 | 0.70 | MAPT (0.49) | MAPTGAAKDM4EALDH1A1CYP1A2 | |
| SCHEMBL29824106 | 0.68 | KDM4E (0.47) | MAPTGAAKDM4EALDH1A1CYP1A2 | |
| SCHEMBL20805456 | 0.68 | KDM4E (0.47) | MAPTGAAKDM4EALDH1A1CYP1A2 | |
| SCHEMBL22720434 | 0.67 | PDE3B (0.43) | MAPTGAAKDM4EALDH1A1CYP1A2 | |
| SCHEMBL28846864 | 0.66 | MAPT (0.33) | MAPTGAAADORA2AADORA1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240182470-A1 | KRASG12C MUTANT PROTEIN INHIBITOR, PREARATION AND USE THEREOF | YA THERAPEUTICS INC (CN) | 2024-06-06 | — | — | US | disclosed |
| CN-115073450-A | KRAS G12C Preparation and application of mutant protein inhibitor | 药雅科技(上海)有限公司 | 2022-09-20 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240182470-A1 | KRASG12C MUTANT PROTEIN INHIBITOR, PREARATION AND USE THEREOF | KRAS, NRAS, HRAS | MAPT 3137/4885GAA 2047/4885KDM4E 3623/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.