SCHEMBL824381

SCHEMBL824381

O=c1[nH]c(=O)c2nc3c(nc2[nH]1)-c1cccc2cccc-3c12

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIK3CG P48736 1/20 0.56
ALDH1A1 P00352 4/20 0.53
BLM P54132 3/20 0.53
TDP1 Q9NUW8 3/20 0.53
KDM4E B2RXH2 3/20 0.53
PABPC1 P11940 2/20 0.53
CASP7 P55210 2/20 0.53
ADORA2B P29275 2/20 0.53
CYP1A2 P05177 2/20 0.53
ADORA2A P29274 1/20 0.53
CYP2C19 P33261 1/20 0.53
RAB9A P51151 1/20 0.53
PMP22 Q01453 1/20 0.53
HSD17B10 Q99714 1/20 0.53
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
MAPT P10636 3/20 0.50
POLB P06746 2/20 0.50
LMNA P02545 1/20 0.50
PKM P14618 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31214529 0.81 ALDH1A1 (0.60) PIK3CGALDH1A1BLMTDP1KDM4E
SCHEMBL13302950 0.78 PIK3CG (0.40) PIK3CGALDH1A1BLMTDP1KDM4E
SCHEMBL10979871 0.76 PIK3CG (0.68) PIK3CGALDH1A1BLMTDP1KDM4E
SCHEMBL23211192 0.71 MAPT (0.64) PIK3CGALDH1A1BLMTDP1KDM4E
SCHEMBL29945196 0.71 MAPT (0.41) PIK3CGALDH1A1BLMTDP1KDM4E
Alloxazine SCHEMBL499075 0.69 KDM4E (1.00) PIK3CGALDH1A1BLMTDP1KDM4E
Alloxazine SCHEMBL29516835 0.69 KDM4E (1.00) PIK3CGALDH1A1BLMTDP1KDM4E
SCHEMBL31214551 0.69 MAPT (0.62) PIK3CGALDH1A1BLMTDP1KDM4E
SCHEMBL23908716 0.69 KDM4E (0.77) PIK3CGALDH1A1BLMTDP1KDM4E
Alloxazine SCHEMBL9619177 0.68 KDM4E (0.96) PIK3CGALDH1A1BLMTDP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3261759-B1 SELF-HEALING CAPACITOR AND METHODS OF PRODUCTION THEREOF CAPACITOR SCIENCES INC (US) 2020-05-06 EP disclosed
US-10347423-B2 Solid multilayer structure as semiproduct for meta-capacitor CAPACITOR SCIENCES INCORPORATED (US) 2019-07-09 US disclosed
US-RE47117-E1 Compensated in-plane switching mode liquid crystal display CRYSOPTIX K.K. (JP) 2018-11-06 US disclosed
US-20180114641-A1 SOLID MULTILAYER STRUCTURE AS SEMIPRODUCT FOR META-CAPACITOR CAPACITOR SCIENCES INCORPORATED 2018-04-26 US disclosed
US-20180114641-A1 SOLID MULTILAYER STRUCTURE AS SEMIPRODUCT FOR META-CAPACITOR CAPACITOR SCIENCES INCORPORATED 2018-04-26 US disclosed
US-9916931-B2 Energy storage devices and methods of production thereof CAPACITOR SCIENCE INCORPORATED (US) 2018-03-13 US disclosed
US-9916931-B2 Energy storage devices and methods of production thereof CAPACITOR SCIENCE INCORPORATED (US) 2018-03-13 US disclosed
US-9852846-B2 Self-healing capacitor and methods of production thereof CAPACITOR SCIENCES INCORPORATED (US) 2017-12-26 US disclosed
US-9852846-B2 Self-healing capacitor and methods of production thereof CAPACITOR SCIENCES INCORPORATED (US) 2017-12-26 US disclosed
EP-2291703-B1 COLOR LIQUID CRYSTAL DISPLAY AND COMPENSATION PANEL CRYSOPTIX KK (JP) 2016-11-30 EP disclosed
US-20100118241-A1 Liquid Crystal Display Operating in a Vertically Aligned Mode CRYSOPTIX KK (JP) 2010-05-13 US disclosed
US-20100118241-A1 Liquid Crystal Display Operating in a Vertically Aligned Mode CRYSOPTIX KK (JP) 2010-05-13 US disclosed
US-20090268136-A1 Color Liquid Crystal Display and Compensation Panel CRYSOPTIX KK (JP) 2009-10-29 US disclosed
WO-2009130676-A2 COLOR LIQUID CRYSTAL DISPLAY AND COMPENSATION PANEL CRYSOPTIX KK (JP) 2009-10-29 WO disclosed
US-20090268136-A1 Color Liquid Crystal Display and Compensation Panel CRYSOPTIX KK (JP) 2009-10-29 US disclosed
WO-2009109782-A2 POLYCYCLIC ORGANIC COMPOUNDS, RETARDATION LAYER AND COMPENSATION PANEL ON THEIR BASE CRYSOPTIX K.K. (JP) 2009-09-11 WO disclosed
US-20090161037-A1 Backlight Module and Liquid Crystal Display Incorporating the Same CRYSOPTIX KK (JP) 2009-06-25 US disclosed
US-20090161037-A1 Backlight Module and Liquid Crystal Display Incorporating the Same CRYSOPTIX KK (JP) 2009-06-25 US disclosed
WO-2009037565-A2 COLOUR LIQUID CRYSTAL DISPLAY AND PATTERNED COMPENSATION PANEL CRYSOPTIX K.K. (GB) 2009-03-26 WO disclosed
WO-2008142635-A2 COMPENSATED IN-PLANE SWITCHING MODE LIQUID CRYSTAL DISPLAY CRYSOPTIX KK (GB) 2008-11-27 WO disclosed